Sugi Predict
/ Targets
/ STK32C
Top predicted compounds (top 20 by supporting neighbours, then confidence)
| Compound | Confidence | Supporting neighbours |
|---|
Clinical trials — most relevant to STK32C by text similarity (a relevance ranking, not an exhaustive list)
| Trial | Phase | Status |
|---|
| Signal TrAnsduction Pathway Activity Analysis in OVarian cancER |
PHASE2/PHASE3 | RECRUITING |
| The G Protein-Coupled Receptor Kinase Type 2 Inhibitor Paroxetine as Adjunctive Therapy to Improve Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus |
PHASE3 | UNKNOWN |
| Combination Treatment (Talazoparib Plus Avelumab) for Stage IV or Recurrent Non-Squamous Non-Small Cell Lung Cancer With STK11 Gene Mutation (A LUNG-MAP Treatment Trial) |
PHASE2 | COMPLETED |
| Study of Efficacy and Safety of JDQ443 Single-agent as First-line Treatment for Patients With Locally Advanced or Metastatic KRAS G12C- Mutated Non-small Cell Lung Cancer With a PD-L1 Expression < 1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation. |
PHASE2 | ACTIVE_NOT_RECRUITING |
| I/II Phase Study Evaluating M1774 in Combination With Fulvestrant in HR+ and HER2- Advanced Breast Cancers |
PHASE1/PHASE2 | NOT_YET_RECRUITING |
| Palbociclib With Fulvestrant for Metastatic Breast Cancer After Treatment With Palbociclib and an Aromatase Inhibitor |
PHASE2 | ACTIVE_NOT_RECRUITING |
| Larotrectinib for the Treatment of NTRK Amplification Positive, Locally Advanced or Metastatic Solid Tumors |
PHASE2 | RECRUITING |
| Metformin Hydrochloride in Preventing Esophageal Cancer in Patients With Barrett Esophagus |
PHASE2 | COMPLETED |
| Everolimus in CDK12-Deficient Metastatic Colorectal Cancer (EVER-RECODE) |
PHASE1/PHASE2 | NOT_YET_RECRUITING |
| Everolimus for Children With Recurrent or Progressive Ependymoma |
PHASE2 | COMPLETED |
| A Broad Multi-histology Phase II Study of the Multi-Kinase Inhibitor R935788 (Fostamatinib Disodium) in Advanced Colorectal, Non-small Cell Lung, Head and Neck Hepatocellular and Renal Cell Carcinomas, and Pheochromocytoma and Thyroid Tumors (Multi-H... |
PHASE2 | COMPLETED |
| Metformin Hydrochloride in Preventing Oral Cancer in Patients With an Oral Premalignant Lesion |
PHASE2 | ACTIVE_NOT_RECRUITING |
| PKC412 and 5-Azacytidine |
PHASE1/PHASE2 | COMPLETED |
| Olaparib in Men With High-Risk Biochemically-Recurrent Prostate Cancer Following Radical Prostatectomy, With Integrated Biomarker Analysis |
PHASE2 | ACTIVE_NOT_RECRUITING |
| Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma |
PHASE1 | COMPLETED |
| A First-in-human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of DS-6051b |
PHASE1 | COMPLETED |
| Chinese Herbal Formulation PHY906 and Sorafenib Tosylate in Treating Patients With Advanced Liver Cancer |
PHASE1 | COMPLETED |
| A Study to Look at the Electrical Activity of the Heart in Subjects With Solid Tumor Cancers, Before and After Receiving the Study Treatment, GSK1120212 |
PHASE1 | COMPLETED |
| Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor, in Combination With Cisplatin in People With Refractory Solid Tumors |
PHASE1 | COMPLETED |
| New Genes in the Carcinogenesis of Colorectal Cancer |
nan | UNKNOWN |
| Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus |
nan | COMPLETED |
| Exercise in Type 1 Diabetes Mellitus |
nan | COMPLETED |
| Dietary Ketosis: Fatty Acids Activate AMPK Energy Circuits Modulating Global Methylation |
nan | COMPLETED |
| Association Between Intakes of Protein, Calcium and Milk With Gene Expression and Linear Growth of School Aged Children |
nan | COMPLETED |
| SMYD3-Driven Metabolic Rewiring in Colorectal Liver Metastases |
nan | NOT_YET_RECRUITING |
| Detection of EGFR Mutation in Malignant Pleural Effusion of Lung Cancer Patients and Cancer Cell Lines Establishment |
nan | UNKNOWN |
| Study Of Real-World Evidence In Patients Treated With Palbociclib During a 2.5 Years Follow-Up Period |
nan | UNKNOWN |
| Protein Intake and Step Reduction in Older Adults |
nan | COMPLETED |
| NTRK 1,2,3 Rearrangements in Patients With Solid Tumors |
nan | ACTIVE_NOT_RECRUITING |
| A Retrospective Clinical Records Review of Patients Diagnosed With Gastrointestinal Stromal Tumour at Two Tertiary Institutes in Singapore |
nan | COMPLETED |
Related proteins — ESM-2 sequence neighbours (a STK32C binder may also engage these)