TFB2M

Dimethyladenosine transferase 2, mitochondrial · Q9H5Q4 · TFB2M on Sugi Atlas →

0 patent compounds predicted against TFB2M, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to TFB2M by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Motor Function Efficacy of Pharmacological Treatments Targeting Energy Metabolism, in Parkinson's Patients PHASE4UNKNOWN
A Study of the Efficacy and Safety of MT1621 in Thymidine Kinase 2 (TK2) Deficiency (Treatment naïve) PHASE3WITHDRAWN
Use of New Drug QRX-3 for Prevention and Treatment of Chronic Kidney Disease Progression PHASE2/PHASE3NOT_YET_RECRUITING
Clinical Evaluation of the Effect of Metformin in Sepsis PHASE3UNKNOWN
A Study of Bezafibrate in Mitochondrial Myopathy PHASE2COMPLETED
Relative Mitochondrial Toxicity of Tenofovir Alafenamide (TAF) vs. Tenofovir Disoproxil Fumarate (TDF) PHASE1/PHASE2COMPLETED
ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma PHASE2COMPLETED
Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D) EARLY_PHASE1COMPLETED
Effectiveness of Light for Enhancement of Cognition by Transcranial Repeated Application (ELECTRA) EARLY_PHASE1COMPLETED
Relationship Between Mitochondrial Dysfunction and Fatique in Cancer Patients Following External Beam Radiation Therapy nanCOMPLETED
Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise nanCOMPLETED
Skeletal Muscle Regeneration in Survivors of Critical Illness: How to Prevent Satellite Cell Failure? nanRECRUITING
Tissue Sample Study for Mitochondrial Disorders nanENROLLING_BY_INVITATION
Pathogenic Insights and Search for Biomarkers in RFC1-ataxia/CANVAS nanRECRUITING
Exercise-mediated Rescue of Mitochondrial Dysfunctions Driving Insulin Resistance nanCOMPLETED
Drug Repurposing for Mitochondrial Disorders Using iPSCs Derived Neural Cells nanRECRUITING
Effect of Branched Chain Amino Acids on Muscle nanCOMPLETED
Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men nanRECRUITING
Clinical Study of Hydroxytyrosol (HT) in Mitochondrial Diseases nanCOMPLETED
Measuring Protein Turnover in Humans Across the Lifespan by Metabolic Labeling With Deuterium Oxide nanRECRUITING
Transgenerational Metabolic-Immune Biomarkers of Neurological and Neurodevelopmental Disorders nanRECRUITING
Mitochondrial Dysfunctions Driving Insulin Resistance nanCOMPLETED
Mitochondrial Dysfunction in Diabetes nanCOMPLETED
Human Mitochondrial Stress-driven Obesity Resistance nanCOMPLETED
Angiogenesis Induced in the Elderly by Hyperbaric Oxygen Therapy nanCOMPLETED
Nicotinamide Riboside and Mitochondrial Biogenesis nanCOMPLETED
Immune Responses With Reduxium nanCOMPLETED
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes nanCOMPLETED
Mitigating Mitochondrial RNA Release During Aging to Control Inflammation and Senescence nanNOT_YET_RECRUITING
Mitochondrial Disease-associated ImmunoDeficiencies nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a TFB2M binder may also engage these)

ProteinNameSimilarity
Q32LD4 1.000 Q32LD4 →
Q3TL26 1.000 Q3TL26 →
Q5U2T7 0.992 Q5U2T7 →
Q91VF2 0.982 Q91VF2 →
Q5SNQ7 0.981 Q5SNQ7 →
Q61586 0.981 Q61586 →
Q5RAY7 0.980 Q5RAY7 →
Q2TB18 0.980 Q2TB18 →
Q8R4Z9 0.980 Q8R4Z9 →
Q2HJE1 0.980 Q2HJE1 →
Q811U4 0.980 Q811U4 →
Q95KD0 0.980 Q95KD0 →
Q9D2K4 0.980 Q9D2K4 →
Q14C51 0.980 Q14C51 →
O15091 0.979 O15091 →
Q14CZ7 0.979 Q14CZ7 →
Q4R366 0.979 Q4R366 →
B5DF07 0.979 B5DF07 →
Q5GJ77 0.979 Q5GJ77 →
Q69LX2 0.979 Q69LX2 →
A0JMU5 0.979 A0JMU5 →
Q761X5 0.979 Q761X5 →
O95185 0.979 O95185 →
PRMT9 Protein arginine N-methyltransferase 9 0.979 landscape →
FASTKD5 FAST kinase domain-containing protein 5, mitochondrial 0.979 landscape →
Q5RCY5 0.979 Q5RCY5 →
Q8JZY4 0.979 Q8JZY4 →
Q9D565 0.979 Q9D565 →
Q3UY23 0.979 Q3UY23 →
Q3U213 0.979 Q3U213 →