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Sugi Predict / Targets / UTP20

UTP20

Small subunit processome component 20 homolog · O75691 · UTP20 on Sugi Atlas →

1,883 patent compounds predicted against UTP20, 1,667 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
Molibresib Molibresib (SCHEMBL1872390) 1.00 1/20
Molibresib Molibresib (SCHEMBL12671490) 1.00 1/20
Molibresib Molibresib (SCHEMBL12966358) 1.00 1/20
SCHEMBL9998851 SCHEMBL9998851 0.91 1/20
SCHEMBL14756282 SCHEMBL14756282 0.88 1/20
SCHEMBL15980874 SCHEMBL15980874 0.88 1/20
SCHEMBL12966165 SCHEMBL12966165 0.87 1/20
SCHEMBL14756215 SCHEMBL14756215 0.87 1/20
SCHEMBL14756339 SCHEMBL14756339 0.87 1/20
SCHEMBL15980861 SCHEMBL15980861 0.87 1/20
SCHEMBL9998825 SCHEMBL9998825 0.86 1/20
SCHEMBL15980893 SCHEMBL15980893 0.86 1/20
SCHEMBL15980803 SCHEMBL15980803 0.86 1/20
SCHEMBL1874116 SCHEMBL1874116 0.85 1/20
SCHEMBL12671221 SCHEMBL12671221 0.85 1/20
SCHEMBL14756021 SCHEMBL14756021 0.85 1/20
SCHEMBL14756240 SCHEMBL14756240 0.85 1/20
SCHEMBL14756287 SCHEMBL14756287 0.85 1/20
SCHEMBL14756335 SCHEMBL14756335 0.85 1/20
SCHEMBL14756409 SCHEMBL14756409 0.85 1/20

Clinical trials — most relevant to UTP20 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Hydroxychloroquine and Metabolic Outcomes in Patients Undergoing TPAIT PHASE2COMPLETED
Histocompatibility Leukocyte Antigen (HLA)-A*0201 Restricted Peptide Vaccine Therapy in Patients With Esophageal Cancer PHASE1/PHASE2COMPLETED
Clinical Study of EBV-LMP1 Targeted DNAzyme to Treat Nasopharyngeal Carcinoma PHASE1/PHASE2COMPLETED
Safety Evaluation of Gene Therapy in Leber Hereditary Optic Neuropathy (LHON) Patients PHASE1/PHASE2COMPLETED
Human Leukocyte Antigen (HLA) - A*2402 Restricted Peptide Vaccine Therapy in Patients With Advanced Esophageal Cancer PHASE1COMPLETED
Human Leukocyte Antigen (HLA) - A*2402 Restricted Peptide Vaccine Therapy in Patients With Advanced Gastric Cancer PHASE1COMPLETED
Peptide Vaccine Targeting to Cancer Specific Antigen Combined With Anti-angiogenic Peptide Antigen in Treating Patients With Non-small Cell Lung Cancer PHASE1COMPLETED
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis nanUNKNOWN
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Identification of the Genetic Causes of Rare Diseases With Negative Exome Findings nanUNKNOWN
Genetic Investigation of Cancer Predisposition nanNOT_YET_RECRUITING
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Exome Analysis in Hearing Impaired Patients nanUNKNOWN
Target of Suv420h1/2 in Hepatocytes nanRECRUITING
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Investigations Into ISCU Myopathy or Iron Sulfur Scaffold U Protein Myopathy nanCOMPLETED
Uncovering the Etiologies of Non-immune Hydrops Fetalis nanENROLLING_BY_INVITATION
Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives nanUNKNOWN
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact nanUNKNOWN
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve nanUNKNOWN
Stress and Treatment Response in Puerto Rican Children With Asthma nanCOMPLETED
Whole Genome Sequencing in the Neonatal Intensive Care Unit nanCOMPLETED
Study of Constitutional Platelet Disease nanUNKNOWN
Study of the Genetic and Epigenetic Causes of Recurrent Hydatidiform Moles nanACTIVE_NOT_RECRUITING
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Identification of New Genes Implicated in Rare Neurosensory Diseases by Whole Exome Sequencing nanUNKNOWN
Phenotypic and Genotypic Characterization of Subjects With Syndromic Obesity: Identifying New Candidate Genes by Exome Sequencing (OBEXOME) nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a UTP20 binder may also engage these)

ProteinNameSimilarity
Q5XG71 — 1.000 Q5XG71 →
E9PVA8 — 0.999 E9PVA8 →
A8WTE8 — 0.998 A8WTE8 →
Q2TAW0 — 0.998 Q2TAW0 →
GCN1 Stalled ribosome sensor GCN1 0.997 landscape →
Q86XI2 — 0.997 Q86XI2 →
Q6DFV1 — 0.997 Q6DFV1 →
P97313 — 0.997 P97313 →
Q5JWR5 — 0.997 Q5JWR5 →
E7FH61 — 0.996 E7FH61 →
Q750S2 — 0.996 Q750S2 →
Q6A009 — 0.996 Q6A009 →
Q9DEI1 — 0.996 Q9DEI1 →
Q4V9P9 — 0.996 Q4V9P9 →
Q5PQS3 — 0.996 Q5PQS3 →
F4IP13 — 0.996 F4IP13 →
Q8IGJ0 — 0.995 Q8IGJ0 →
Q19317 — 0.995 Q19317 →
E1C231 — 0.995 E1C231 →
Q6PR54 — 0.995 Q6PR54 →
Q14D04 — 0.995 Q14D04 →
Q9V677 — 0.994 Q9V677 →
Q8BZM1 — 0.994 Q8BZM1 →
Q3URQ0 — 0.994 Q3URQ0 →
Q9VJ29 — 0.994 Q9VJ29 →
Q9Y3R5 — 0.994 Q9Y3R5 →
F6WXT2 — 0.993 F6WXT2 →
Q8INF7 — 0.993 Q8INF7 →
Q61037 — 0.993 Q61037 →
Q14156 — 0.993 Q14156 →