Beta-2'-C-Methyl-7-Deaza-Adenosine

Beta-2'-C-Methyl-7-Deaza-Adenosine

SCHEMBL733423

C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1ccc2c(N)ncnc21

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 4/20 0.67
PRMT5 O14744 12/20 0.57
WDR77 Q9BQA1 12/20 0.57
ADK P55263 1/20 0.53
ADORA3 P0DMS8 4/20 0.52
ADA P00813 1/20 0.48
ADORA2B P29275 1/20 0.48
ADORA1 P30542 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL13772636 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL14628545 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL731022 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL12150774 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL14628542 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL14081715 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL13055908 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL15093204 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL18661674 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL14640071 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 555 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4566670-A2 MODULATORS OF PHARMACOKINETIC PROPERTIES OF THERAPEUTICS Gilead Sciences, Inc. (US) 2025-06-11 EP claimed
CN-118812615-A 7-Denitrification-2' -C-methyl adenosine phosphoramidite monomer and synthesis method thereof 江苏合甘元生物科技有限公司 2024-10-22 CN claimed
EP-4403221-A2 MODULATORS OF PHARMACOKINETIC PROPERTIES OF THERAPEUTICS Gilead Sciences, Inc. (US) 2024-07-24 EP claimed
US-20230372370-A1 USE OF CANNABINOIDS IN THE TREATMENT OF COVID-19 Orcosa Inc. (US) 2023-11-23 US claimed
US-20230142126-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF VIRAL DISEASES HEALION BIO., INC. (US) 2023-05-11 US claimed
EP-4149552-A1 COMPOSITIONS AND METHODS FOR INCREASING EFFICACY OF A DRUG Healion Bio, Inc. (US) 2023-03-22 EP claimed
CN-114641299-A Methods for treating SARS CoV-2 infection 吉利德科学公司 2022-06-17 CN claimed
EP-2680859-B1 COMPOSITIONS, METHODS OF TREATMENT AND DIAGNOSTICS FOR TREATMENT OF HEPATIC STEATOSIS ALONE OR IN COMBINATION WITH A HEPATITIS C VIRUS INFECTION SCHENTAG JEROME (US) 2022-04-27 EP claimed
CN-114273182-A Coating and cooking utensil 武汉苏泊尔炊具有限公司 2022-04-05 CN claimed
EP-3963087-A1 IDENTIFICATION AND ANALYSIS OF MICROBIAL SAMPLES BY RAPID INCUBATION AND NUCLEIC ACID ENRICHMENT Illumina Inc (US) 2022-03-09 EP claimed
US-20050272676-A1 Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase BHAT BALKRISHEN 2005-12-08 US claimed
US-20050164960-A1 Methods of inhibiting orthopoxvirus replication with nucleoside compounds MERCK SHARP & DOHME CORP. 2005-07-28 US claimed
US-20040259934-A1 Inhibiting Coronaviridae viral replication and treating Coronaviridae viral infection with nucleoside compounds OLSEN DAVID B (US) 2004-12-23 US claimed
EP-1476169-A1 METHODS OF INHIBITING ORTHOPOXVIRUS REPLICATION WITH NUCLEOSIDE COMPOUNDS Merck & Co., Inc. (US) 2004-11-17 EP claimed
US-6777395-B2 VIRICIDES MERCK & CO., INC. 2004-08-17 US claimed
CN-1498221-A Nucleoside derivatives as inhibitors of RNA-dependent PNA viral polymerase 2004-05-19 CN claimed
US-20040072788-A1 Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase BHAT BALKRISHEN (US) 2004-04-15 US claimed
US-20040067901-A1 Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase MERCK SHARP & DOHME LLC 2004-04-08 US claimed
WO-2003068244-A1 METHODS OF INHIBITING ORTHOPOXVIRUS REPLICATION WITH NUCLEOSIDE COMPOUNDS MERCK & CO., INC. (US) 2003-08-21 WO claimed
US-20020147160-A1 Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase MERCK SHARP & DOHME LLC 2002-10-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040067901-A1 Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase NSUN2, NSUN3, POLRMT ADORA2A 416/4885PRMT5 436/4885WDR77 1478/4885
US-20230142126-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF VIRAL DISEASES CTSV, CTSB, CTSS ADORA2A 2823/4885PRMT5 2463/4885WDR77 1820/4885
US-20040072788-A1 Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase NSUN2, NSUN3, POLRMT ADORA2A 416/4885PRMT5 436/4885WDR77 1478/4885
US-20050272676-A1 Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase NSUN2, NSUN3, POLRMT ADORA2A 416/4885PRMT5 436/4885WDR77 1478/4885
US-20040259934-A1 Inhibiting Coronaviridae viral replication and treating Coronaviridae viral infection with nucleoside compounds SARS1, ACE, ACE2 ADORA2A 421/4885PRMT5 1170/4885WDR77 2008/4885
US-20020147160-A1 Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase NSUN2, NSUN3, POLRMT ADORA2A 416/4885PRMT5 436/4885WDR77 1478/4885
US-20050164960-A1 Methods of inhibiting orthopoxvirus replication with nucleoside compounds ITPA, PNP, NUDT1 ADORA2A 192/4885PRMT5 1470/4885WDR77 1575/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.