ZFP91

E3 ubiquitin-protein ligase ZFP91 · Q96JP5 · ZFP91 on Sugi Atlas →

2,097 patent compounds predicted against ZFP91, 1,748 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
Bufalin Bufalin (SCHEMBL165666) 1.00 1/20
Bufalin Bufalin (SCHEMBL8257006) 1.00 1/20
Bufalin Bufalin (SCHEMBL1346952) 0.93 1/20
Bufalin Bufalin (SCHEMBL11205069) 0.85 1/20
SCHEMBL1483968 SCHEMBL1483968 0.76 1/20
Gamabufotalin Gamabufotalin (SCHEMBL866038) 0.75 1/20
Gamabufotalin Gamabufotalin (SCHEMBL866039) 0.75 1/20
Gamabufotalin Gamabufotalin (SCHEMBL1484413) 0.75 1/20
SCHEMBL1483302 SCHEMBL1483302 0.75 1/20
SCHEMBL1483359 SCHEMBL1483359 0.75 1/20
SCHEMBL1483677 SCHEMBL1483677 0.75 1/20
SCHEMBL5082699 SCHEMBL5082699 0.75 1/20
SCHEMBL1484109 SCHEMBL1484109 0.74 1/20
SCHEMBL1483701 SCHEMBL1483701 0.74 1/20
SCHEMBL3364225 SCHEMBL3364225 0.74 1/20
SCHEMBL3364229 SCHEMBL3364229 0.74 1/20
SCHEMBL7286202 SCHEMBL7286202 0.74 1/20
SCHEMBL7286487 SCHEMBL7286487 0.74 1/20
SCHEMBL12038720 SCHEMBL12038720 0.74 1/20
SCHEMBL12057551 SCHEMBL12057551 0.74 1/20

Clinical trials — most relevant to ZFP91 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Mechanisms of Lipodystrophy in HIV-Infected Pateints PHASE4COMPLETED
Can We Achieve 'high-quality' Weight Loss Through Supplementation and Exercise? the TRIM MUSCLE Study PHASE3COMPLETED
The Use of Inhaled Corticosteroids in the Treatment of Asthma is Children in the Emergency Room PHASE2/PHASE3COMPLETED
Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers PHASE2NOT_YET_RECRUITING
Safety and Dose Escalation Study of Zinc Supplementation in Critically Ill Children PHASE1/PHASE2COMPLETED
Testing the Combination of MLN4924 (Pevonedistat), Carboplatin, and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Who Have Previously Been Treated With Immunotherapy PHASE2ACTIVE_NOT_RECRUITING
Value of Using Pioglitazone in Chronic Myeloid Leukemia Treatment PHASE2COMPLETED
Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage Mesothelioma PHASE2WITHDRAWN
A Study of Bezafibrate in Mitochondrial Myopathy PHASE2COMPLETED
Decitabine in Treating Patients With Myelofibrosis PHASE2ACTIVE_NOT_RECRUITING
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck PHASE1COMPLETED
EKLF Gene Expression in β-thalassemia nanNOT_YET_RECRUITING
Genetic Variation in TRAF3IP2 (rs13190932) nanRECRUITING
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia nanUNKNOWN
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis nanUNKNOWN
RORC Genetic Polymorphism of Rheumatoid Arthritis nanCOMPLETED
Evaluation of the Predictive Effect of Inflammatory Markers in MI Patients nanUNKNOWN
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders nanCOMPLETED
Mitochondrial Activity and Myosteatosis in the Cachexia of Cancers of the Upper Aerodigestive Tract nanUNKNOWN
Natural History Study of GATA2 Deficiency and Related Disorders nanRECRUITING
Cell Signaling and Resistance to Oxidative Stress: Effects of Aging and Exercise nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Gene Expression Variation and Implant Wound Healing Among Smokers and Diabetics nanCOMPLETED
Analysis of the Role of AIRE in Autoimmune Neurological Diseases Associated With Autoantibodies nanRECRUITING
Treatment Strategy to Enhance Nrf2 Signaling in Older Adults nanCOMPLETED
Germline Alterations of Tumor Susceptibility Genes in New York Cancer Patients nanACTIVE_NOT_RECRUITING
Studies on the Expression and Functions of RLIP76 in Blood Samples of Healthy Human Subjects nanWITHDRAWN
A Study to See if Low Level Laser Light Therapy (LLLT) Can Improve the Condition of Nonalcoholic Steatohepatitis (NASH) nanWITHDRAWN
Azoospermia Patients nanRECRUITING
Identification and Metabolic Characterization of a Cohort of Human Subjects With Mutations in PRDM-16 nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a ZFP91 binder may also engage these)

ProteinNameSimilarity
Q62511 1.000 Q62511 →
A4FV61 0.980 A4FV61 →
Q8K2W6 0.979 Q8K2W6 →
Q8CE64 0.978 Q8CE64 →
Q92667 0.978 Q92667 →
Q9WU42 0.977 Q9WU42 →
Q9BE73 0.976 Q9BE73 →
D4A7U2 0.976 D4A7U2 →
Q5U2T6 0.976 Q5U2T6 →
P39881 0.976 P39881 →
Q5R6F3 0.975 Q5R6F3 →
Q9QYE0 0.975 Q9QYE0 →
Q9Z2D6 0.975 Q9Z2D6 →
Q17R98 0.975 Q17R98 →
Q99NA2 0.975 Q99NA2 →
F7AQ22 0.974 F7AQ22 →
Q96ME7 0.974 Q96ME7 →
Q6NXK2 0.974 Q6NXK2 →
Q8CDC7 0.974 Q8CDC7 →
Q5XJV7 0.974 Q5XJV7 →
Q5TC79 0.973 Q5TC79 →
NCOR2 Nuclear receptor corepressor 2 0.973 landscape →
Q4V7B1 0.973 Q4V7B1 →
Q8WY91 0.973 Q8WY91 →
BRD8 Bromodomain-containing protein 8 0.973 landscape →
Q8BSV3 0.973 Q8BSV3 →
P97432 0.972 P97432 →
Q505G8 0.972 Q505G8 →
Q96C00 0.972 Q96C00 →
Q9NQV5 0.972 Q9NQV5 →