Sugi Predict

Sugi Predict / Compounds / SCHEMBL10000140

SCHEMBL10000140

SCHEMBL10000140

C/C(C=O)=C\CC/C(C)=C/CCC(C)(C)[Si](O)(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.34
▸ TSHR P16473 2/20 0.34
▸ LMNA P02545 2/20 0.34
▸ CYP1A2 P05177 2/20 0.34
▸ CYP3A4 P08684 2/20 0.34
▸ CYP2C9 P11712 2/20 0.34
▸ HIF1A Q16665 2/20 0.34
▸ ICMT O60725 1/20 0.34
▸ GMNN O75496 1/20 0.34
▸ TRPA1 O75762 1/20 0.34
▸ POLB P06746 1/20 0.34
▸ NFKB1 P19838 1/20 0.34
▸ CDK2 P24941 1/20 0.34
▸ RECQL P46063 1/20 0.34
▸ BLM P54132 1/20 0.34
▸ HSD17B10 Q99714 1/20 0.34
▸ ALOX15 P16050 3/20 0.33
▸ TRPV1 Q8NER1 2/20 0.33
▸ PGR P06401 1/20 0.33
▸ HTR1A P08908 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10000060 0.91 HPGD (0.40) MAPTTSHRLMNACYP1A2CYP3A4
SCHEMBL10000059 0.87 ALOX15 (0.46) MAPTTSHRLMNACYP1A2CYP3A4
SCHEMBL16664317 0.86 PTGS2 (0.36) MAPTTSHRLMNACYP1A2CYP3A4
SCHEMBL12059194 0.81 MAPT (0.42) MAPTTSHRLMNACYP1A2CYP3A4
SCHEMBL10000084 0.80 DHODH (0.32) MAPTTSHRLMNACYP1A2CYP3A4
SCHEMBL10000062 0.80 DHODH (0.32) MAPTTSHRLMNACYP1A2CYP3A4
SCHEMBL10000066 0.80 DHODH (0.32) MAPTTSHRLMNACYP1A2CYP3A4
SCHEMBL12059204 0.80 MAPT (0.33) MAPTTSHRLMNACYP1A2CYP3A4
SCHEMBL10000064 0.79 LSS (0.48) —
SCHEMBL14303767 0.79 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9657313-B2 Isoprene oligomer, polyisoprene, processes for producing these materials, rubber composition, and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2017-05-23 — — US disclosed
US-20160222418-A1 ISOPRENE OLIGOMER, POLYISOPRENE, PROCESSES FOR PRODUCING THESE MATERIALS, RUBBER COMPOSITION, AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-08-04 — — US disclosed
US-20140171675-A1 ISOPRENE OLIGOMER, POLYISOPRENE, PROCESSES FOR PRODUCING THESE MATERIALS, RUBBER COMPOSITION, AND PNEUMATIC TIRE YAMAGATA UNIVERSITY (JP) 2014-06-19 — — US disclosed
EP-2594597-A1 ISOPRENE OLIGOMER, POLYISOPRENE, PROCESSES FOR PRODUCING THESE MATERIALS, RUBBER COMPOSITION, AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2013-05-22 — — EP disclosed
WO-2012008298-A1 ISOPRENE OLIGOMER, POLYISOPRENE, PROCESSES FOR PRODUCING THESE MATERIALS, RUBBER COMPOSITION, AND PNEUMATIC TIRE 住友ゴム工業株式会社 (JP) 2012-01-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140171675-A1 ISOPRENE OLIGOMER, POLYISOPRENE, PROCESSES FOR PRODUCING THESE MATERIALS, RUBBER COMPOSITION, AND PNEUMATIC TIRE RCE1, GGPS1, TELO2 MAPT 3569/4885TSHR 3407/4885LMNA 586/4885
US-20160222418-A1 ISOPRENE OLIGOMER, POLYISOPRENE, PROCESSES FOR PRODUCING THESE MATERIALS, RUBBER COMPOSITION, AND PNEUMATIC TIRE RCE1, GGPS1, TELO2 MAPT 3569/4885TSHR 3407/4885LMNA 586/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.