Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | BTN3A1 | O00481 | 4/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10000059 | 0.90 | ALOX15 (0.46) | ALOX15MAPTCYP3A4ICMTGMNN | |
| SCHEMBL10000060 | 0.89 | HPGD (0.40) | ALOX15MAPTCYP3A4ICMTGMNN | |
| SCHEMBL12059194 | 0.86 | MAPT (0.42) | ALOX15MAPTCYP3A4ICMTGMNN | |
| SCHEMBL10000140 | 0.86 | MAPT (0.34) | ALOX15BTN3A1MAPTCYP3A4ICMT | |
| SCHEMBL10000084 | 0.83 | DHODH (0.32) | ALOX15MAPTCYP3A4ICMTGMNN | |
| SCHEMBL10000062 | 0.83 | DHODH (0.32) | ALOX15MAPTCYP3A4ICMTGMNN | |
| SCHEMBL10000066 | 0.83 | DHODH (0.32) | ALOX15MAPTCYP3A4ICMTGMNN | |
| SCHEMBL12059204 | 0.83 | MAPT (0.33) | ALOX15MAPTCYP3A4ICMTGMNN | |
| SCHEMBL10000064 | 0.82 | LSS (0.48) | — | |
| SCHEMBL14303767 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160257983-A1 | N-GLYCOSYLATION OF PEPTIDES AND PROTEINS | ISIS INNOVATION LIMITED (GB) | 2016-09-08 | — | — | US | disclosed |
| WO-2015056011-A1 | N-GLYCOSYLATION OF PEPTIDES AND PROTEINS | ISIS INNOVATION LIMITED (GB) | 2015-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160257983-A1 | N-GLYCOSYLATION OF PEPTIDES AND PROTEINS | PTMS, PGLS, PSPH | PTGS2 4510/4885ALOX15 4287/4885BTN3A1 3284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.