Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | CDC25C | P30307 | 1/20 | 0.41 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6764921 | 0.79 | ALDH1A1 (0.57) | ALDH1A1HPGDKDM4EHTTSMN1; SMN2 | |
| SCHEMBL2222584 | 0.79 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4EHTTSMN1; SMN2 | |
| SCHEMBL15106404 | 0.79 | KDM4E (0.48) | ALDH1A1HPGDKDM4EHTTSMN1; SMN2 | |
| SCHEMBL15106909 | 0.77 | KDM4E (0.47) | ALDH1A1HPGDKDM4EHTTSMN1; SMN2 | |
| SCHEMBL15106908 | 0.77 | KDM4E (0.47) | ALDH1A1HPGDKDM4EHTTSMN1; SMN2 | |
| SCHEMBL17367229 | 0.77 | KDM4E (0.61) | ALDH1A1HPGDKDM4EHTTSMN1; SMN2 | |
| SCHEMBL15106529 | 0.75 | CYP1A2 (0.47) | ALDH1A1HPGDKDM4EHTTSMN1; SMN2 | |
| SCHEMBL15106814 | 0.74 | CYP1A1 (0.46) | ALDH1A1HPGDKDM4EHTTSMN1; SMN2 | |
| SCHEMBL30526453 | 0.74 | CYP1A1 (0.46) | ALDH1A1HPGDKDM4EHTTSMN1; SMN2 | |
| SCHEMBL15106816 | 0.74 | CYP1A1 (0.46) | ALDH1A1HPGDKDM4EHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012017876-A1 | P2X4 RECEPTOR ANTAGONIST | 日本ケミファ株式会社 (JP) | 2012-02-09 | — | — | WO | disclosed |