SCHEMBL17367229

SCHEMBL17367229

O=c1nc(-c2ccccc2)c2ccc3ccccc3c2[nH]1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.61
ALDH1A1 P00352 6/20 0.61
HSD17B10 Q99714 5/20 0.61
HPGD P15428 5/20 0.61
TSHR P16473 2/20 0.61
KMT2A Q03164 4/20 0.49
NPSR1 Q6W5P4 3/20 0.49
MEN1 O00255 3/20 0.49
CASP1 P29466 1/20 0.49
PDE3B Q13370 2/20 0.47
PDE3A Q14432 2/20 0.47
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
KIF11 P52732 1/20 0.46
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
MAPT P10636 2/20 0.42
GLA P06280 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MCL1 Q07820 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15106404 0.88 KDM4E (0.48) KDM4EALDH1A1HSD17B10HPGDTSHR
SCHEMBL15106909 0.87 KDM4E (0.47) KDM4EALDH1A1HSD17B10HPGDTSHR
SCHEMBL15106908 0.87 KDM4E (0.47) KDM4EALDH1A1HSD17B10HPGDTSHR
SCHEMBL15106339 0.84 KMT2A (0.58) KDM4EALDH1A1HSD17B10HPGDTSHR
SCHEMBL15106529 0.84 CYP1A2 (0.47) KDM4EALDH1A1HSD17B10HPGDTSHR
SCHEMBL15106793 0.84 AURKA (0.46) KDM4EALDH1A1HSD17B10HPGDTSHR
SCHEMBL15106605 0.84 IDO1 (0.45) KDM4EALDH1A1HSD17B10HPGDTSHR
Hydrochloric Acid SCHEMBL15106818 0.83 AURKA (0.45) KDM4EALDH1A1HSD17B10HPGDTSHR
SCHEMBL15106814 0.83 CYP1A1 (0.46) KDM4EALDH1A1HSD17B10HPGDTSHR
SCHEMBL30526453 0.83 CYP1A1 (0.46) KDM4EALDH1A1HSD17B10HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111377872-A Synthesis method of 2-chloro-4-phenylbenzoquinazoline 广东阿格蕾雅光电材料有限公司 2020-07-07 CN claimed
US-10749118-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-08-18 US disclosed
CN-111377872-A Synthesis method of 2-chloro-4-phenylbenzoquinazoline 广东阿格蕾雅光电材料有限公司 2020-07-07 CN disclosed
US-10651397-B2 Organic light emitting compound and organic light emitting device comprising the same SFC CO., LTD. (KR) 2020-05-12 US disclosed
US-20180072753-A1 NOVEL ORGANIC HETEROCYCLIC COMPOUND AND LIGHT-EMITTING DEVICE COMPRISING SAME SFC CO., LTD. (KR) 2018-03-15 US disclosed
US-20180072753-A1 NOVEL ORGANIC HETEROCYCLIC COMPOUND AND LIGHT-EMITTING DEVICE COMPRISING SAME SFC CO., LTD. (KR) 2018-03-15 US disclosed
EP-3135676-A1 ELECTROLUMINESCENT ORGANIC COMPOUNDS FOR ORGANIC ELECTRIC ELEMENTS AND ELECTRONIC DEVICES Duk San Neolux Co., Ltd. (KR) 2017-03-01 EP disclosed
US-9508939-B2 Compound and organic electroluminescent element produced using same IDEMITSU KOSAN CO., LTD. (JP) 2016-11-29 US disclosed
US-9508939-B2 Compound and organic electroluminescent element produced using same IDEMITSU KOSAN CO., LTD. (JP) 2016-11-29 US disclosed
US-9466803-B1 Compound for organic electric element, organic electric element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2016-10-11 US disclosed
US-9466803-B1 Compound for organic electric element, organic electric element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2016-10-11 US disclosed
US-20160260906-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME SFC CO., LTD. (KR) 2016-09-08 US disclosed
US-20160260906-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME SFC CO., LTD. (KR) 2016-09-08 US disclosed
US-20160248024-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME SFC CO., LTD. (KR) 2016-08-25 US disclosed
US-20160248024-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME SFC CO., LTD. (KR) 2016-08-25 US disclosed
US-20160172604-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT PRODUCED USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-06-16 US disclosed
US-20160172604-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT PRODUCED USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-06-16 US disclosed
US-20150380663-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-31 US disclosed
US-20150380663-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160260906-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CRY1, CRY2, MAP1LC3A KDM4E 1811/4885ALDH1A1 196/4885HSD17B10 3323/4885
US-20180072753-A1 NOVEL ORGANIC HETEROCYCLIC COMPOUND AND LIGHT-EMITTING DEVICE COMPRISING SAME OR10J3, CRY1, NR2E3 KDM4E 1697/4885ALDH1A1 133/4885HSD17B10 1925/4885
US-20160172604-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT PRODUCED USING SAME L1CAM, LEF1, EML4 KDM4E 2236/4885ALDH1A1 248/4885HSD17B10 3154/4885
US-10651397-B2 Organic light emitting compound and organic light emitting device comprising the same MAP1LC3C, CRY1, MAP1LC3A KDM4E 2510/4885ALDH1A1 459/4885HSD17B10 4159/4885
US-20160248024-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME MAP1LC3C, CRY1, MAP1LC3A KDM4E 2510/4885ALDH1A1 459/4885HSD17B10 4159/4885
US-20150380663-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CYP1A1, CRY1, CYP1B1 KDM4E 3404/4885ALDH1A1 13/4885HSD17B10 1315/4885
US-10749118-B2 Heterocyclic compound and organic light-emitting device including the same CYP1A1, CRY1, CYP1B1 KDM4E 3404/4885ALDH1A1 13/4885HSD17B10 1315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.