Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TNKS | O95271 | 3/20 | 0.43 |
| ▸ | PARP1 | P09874 | 3/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.43 |
| ▸ | GUSB | P08236 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15106404 | 0.99 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL15106908 | 0.97 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL17367229 | 0.87 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL15106816 | 0.85 | CYP1A1 (0.46) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL30526453 | 0.85 | CYP1A1 (0.46) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL15106529 | 0.84 | CYP1A2 (0.47) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL15106814 | 0.83 | CYP1A1 (0.46) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL15106339 | 0.81 | KMT2A (0.58) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL10000173 | 0.77 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL15106605 | 0.76 | IDO1 (0.45) | KDM4EALDH1A1HPGDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12233071-B2 | Medicament for treating cough | NIPPON CHEMIPHAR CO., LTD. (JP) | 2025-02-25 | — | — | US | disclosed |
| US-11918589-B2 | Medicament for treatment of multiple sclerosis | NIPPON CHEMIPHAR CO., LTD. (JP) | 2024-03-05 | — | — | US | disclosed |
| US-20230248738-A1 | MEDICAMENT FOR TREATING COUGH | NIPPON CHEMIPHAR CO., LTD (JP) | 2023-08-10 | — | — | US | disclosed |
| US-11666582-B2 | Medicament for treating cough | NIPPON CHEMIPHAR CO., LTD. (JP) | 2023-06-06 | — | — | US | disclosed |
| US-20210121478-A1 | MEDICAMENT FOR TREATMENT OF MULTIPLE SCLEROSIS | NIPPON CHEMIPHAR CO., LTD. (JP) | 2021-04-29 | — | — | US | disclosed |
| EP-2617717-B1 | P2X4 RECEPTOR ANTAGONIST | NIPPON CHEMIPHAR CO (JP) | 2016-03-02 | — | — | EP | disclosed |
| US-8680110-B2 | P2X4 receptor antagonist | NIPPON CHEMIPHAR CO., LTD. (JP) | 2014-03-25 | — | — | US | disclosed |
| EP-2617717-A1 | P2X4 RECEPTOR ANTAGONIST | Nippon Chemiphar Co., Ltd. (JP) | 2013-07-24 | — | — | EP | disclosed |
| US-20130184459-A1 | P2X4 RECEPTOR ANTAGONIST | NIPPON CHEMIPHAR CO., LTD. (JP) | 2013-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12233071-B2 | Medicament for treating cough | P2RX4, P2RX3, P2RX5 | KDM4E 4410/4885ALDH1A1 1952/4885HPGD 1051/4885 |
| US-20130184459-A1 | P2X4 RECEPTOR ANTAGONIST | P2RX4, P2RX1, P2RX3 | KDM4E 4019/4885ALDH1A1 2135/4885HPGD 884/4885 |
| US-20210121478-A1 | MEDICAMENT FOR TREATMENT OF MULTIPLE SCLEROSIS | TRPM4, TRPM7, P2RX3 | KDM4E 3758/4885ALDH1A1 2329/4885HPGD 712/4885 |
| US-11918589-B2 | Medicament for treatment of multiple sclerosis | P2RX3, TRPM4, P2RX4 | KDM4E 3715/4885ALDH1A1 2360/4885HPGD 712/4885 |
| US-11666582-B2 | Medicament for treating cough | P2RX4, P2RX3, P2RX5 | KDM4E 4410/4885ALDH1A1 1952/4885HPGD 1051/4885 |
| US-20230248738-A1 | MEDICAMENT FOR TREATING COUGH | P2RX4, P2RX3, P2RX5 | KDM4E 4410/4885ALDH1A1 1952/4885HPGD 1051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.