SCHEMBL10000248

SCHEMBL10000248

Cc1ccc(-c2ccc(-c3ccc(C)cn3)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.68
CCR5 P51681 1/20 0.68
CCR8 P51685 1/20 0.68
HDAC6 Q9UBN7 1/20 0.68
CYP3A4 P08684 1/20 0.57
CYP2A6 P11509 1/20 0.57
KDM1A O60341 1/20 0.53
METAP2 P50579 2/20 0.48
METAP1 P53582 1/20 0.47
AURKA O14965 1/20 0.46
ABL1 P00519 1/20 0.46
NTRK1 P04629 1/20 0.46
LCK P06239 1/20 0.46
CSF1R P07333 1/20 0.46
RET P07949 1/20 0.46
MET P08581 1/20 0.46
PDGFRB P09619 1/20 0.46
PIM1 P11309 1/20 0.46
PDGFRA P16234 1/20 0.46
FLT3 P36888 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2477927 0.98 CCR1 (0.71) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL17051514 0.95 CCR1 (0.75) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL17051522 0.93 CCR1 (0.65) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL12846431 0.91 CCR1 (0.62) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL10000250 0.91 CCR1 (0.54) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL12359222 0.89 CYP3A4 (0.61) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL14804374 0.88 CCR1 (0.73) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL17051517 0.87 CCR1 (0.58) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL6015197 0.86 CCR1 (0.70) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL14804380 0.86 CCR1 (0.76) CCR1CCR5CCR8HDAC6CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10038143-B2 Polymer compound, material for electronic elements, material for organic electroluminescent elements, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-07-31 US disclosed
US-20150249215-A1 POLYMER COMPOUND, MATERIAL FOR ELECTRONIC ELEMENTS, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-09-03 US disclosed
US-8158020-B2 Liquid crystal element, optical path deflecting element, and image displaying apparatus RICOH COMPANY, LTD. (JP) 2012-04-17 US disclosed
US-8158020-B2 Liquid crystal element, optical path deflecting element, and image displaying apparatus RICOH COMPANY, LTD. (JP) 2012-04-17 US disclosed
US-20080204608-A1 Liquid Crystal Element, Optical Path Deflecting Element, and Image Displaying Apparatus RICOH COMPANY, LTD. (JP) 2008-08-28 US disclosed
US-20080204608-A1 Liquid Crystal Element, Optical Path Deflecting Element, and Image Displaying Apparatus RICOH COMPANY, LTD. (JP) 2008-08-28 US disclosed
US-7195719-B1 High polarization ferroelectric liquid crystal compositions DISPLAYTECH, INC. (US) 2007-03-27 US disclosed
US-7195719-B1 High polarization ferroelectric liquid crystal compositions DISPLAYTECH, INC. (US) 2007-03-27 US disclosed