SCHEMBL2477927

SCHEMBL2477927

Cc1ccc(-c2ccc(C)cn2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.71
CCR5 P51681 1/20 0.71
CCR8 P51685 1/20 0.71
HDAC6 Q9UBN7 1/20 0.71
CYP3A4 P08684 1/20 0.59
CYP2A6 P11509 1/20 0.59
KDM1A O60341 1/20 0.55
METAP2 P50579 2/20 0.50
METAP1 P53582 1/20 0.48
AURKA O14965 1/20 0.47
ABL1 P00519 1/20 0.47
NTRK1 P04629 1/20 0.47
LCK P06239 1/20 0.47
CSF1R P07333 1/20 0.47
RET P07949 1/20 0.47
MET P08581 1/20 0.47
PDGFRB P09619 1/20 0.47
PIM1 P11309 1/20 0.47
PDGFRA P16234 1/20 0.47
FLT3 P36888 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10000248 0.98 CCR1 (0.68) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL17051514 0.97 CCR1 (0.75) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL17051522 0.95 CCR1 (0.65) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL6015197 0.89 CCR1 (0.70) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL12846431 0.89 CCR1 (0.62) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL10000250 0.88 CCR1 (0.54) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL14804380 0.88 CCR1 (0.76) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL14804384 0.88 CCR1 (0.56) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL17051539 0.87 CCR1 (0.60) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL22237838 0.87 CCR1 (0.60) CCR1CCR5CCR8HDAC6CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 354 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3816175-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2024-07-17 EP disclosed
CN-118324820-A Organic phosphorescent material, organic electroluminescent device comprising same and organic electroluminescent device 吉林奥来德光电材料股份有限公司 2024-07-12 CN disclosed
US-12022832-B2 Compounds and methods for treating nematode infections THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2024-07-02 US disclosed
CN-118084979-A Organometallic complex, application thereof, organic photoelectric device and device 浙江华显光电科技有限公司 2024-05-28 CN disclosed
CN-117843690-A Organic metal compound, preparation method thereof and organic electroluminescent device 吉林奥来德光电材料股份有限公司 2024-04-09 CN disclosed
CN-117263992-B Organic metal compound and organic electroluminescent device comprising same 吉林奥来德光电材料股份有限公司 2024-03-26 CN disclosed
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
CN-117263992-A Organic metal compound and organic electroluminescent device comprising same 吉林奥来德光电材料股份有限公司 2023-12-22 CN disclosed
US-11827651-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
US-20230374049-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2023-11-23 US disclosed
US-7220820-B2 Electroactive fluorene copolymers and devices made with such polymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-05-22 US disclosed
US-7214763-B2 Electroactive fluorene copolymers and devices made with such polymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-05-08 US disclosed
US-7211643-B2 Electroactive fluorene copolymers and devices made with such polymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-05-01 US disclosed
US-7195719-B1 High polarization ferroelectric liquid crystal compositions DISPLAYTECH, INC. (US) 2007-03-27 US disclosed
US-7195719-B1 High polarization ferroelectric liquid crystal compositions DISPLAYTECH, INC. (US) 2007-03-27 US disclosed
EP-1763902-A2 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS Universal Display Corporation (US) 2007-03-21 EP disclosed
US-7183365-B2 Electroactive fluorene polymers having perfluoroalkyl groups, process for preparing such polymers and devices made with such polymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-02-27 US disclosed
US-7183366-B2 Aromatic copolymers from dihalofluorene compounds and another dihalo- or diborono- aromatic monomers; organic electroluminescent polymers for use in light-emitting diodes E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-02-27 US disclosed
US-20070003789-A1 Stable and efficient electroluminescent materials UNIVERSAL DISPLAY CORPORAITON 2007-01-04 US disclosed
WO-2006014599-A2 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2006-02-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12022832-B2 Compounds and methods for treating nematode infections HNMT, NISCH, HRH2 CCR1 1016/4885CCR5 1571/4885CCR8 1321/4885
US-20230374049-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING ORGANOMETALLIC COMPOUND NOM1, MSL1, L1CAM CCR1 2485/4885CCR5 3562/4885CCR8 4316/4885
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP CCR1 2004/4885CCR5 786/4885CCR8 869/4885
US-11827651-B2 Organic electroluminescent materials and devices SSB, L1CAM, LEF1 CCR1 1383/4885CCR5 2168/4885CCR8 1196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.