SCHEMBL6015197

SCHEMBL6015197

Cc1ccc(-c2cnc(-c3ccc(C)cn3)cn2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.70
CCR5 P51681 1/20 0.70
CCR8 P51685 1/20 0.70
HDAC6 Q9UBN7 1/20 0.70
METAP2 P50579 2/20 0.50
CYP3A4 P08684 1/20 0.48
CYP2A6 P11509 1/20 0.48
KDM1A O60341 1/20 0.46
METAP1 P53582 1/20 0.44
NOS3 P29474 1/20 0.41
NOS2 P35228 1/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
LMNA P02545 2/20 0.41
GRM5 P41594 2/20 0.41
AURKA O14965 1/20 0.41
ABL1 P00519 1/20 0.41
NTRK1 P04629 1/20 0.41
LCK P06239 1/20 0.41
CSF1R P07333 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2477927 0.89 CCR1 (0.71) CCR1CCR5CCR8HDAC6METAP2
SCHEMBL10205815 0.89 CCR1 (0.55) CCR1CCR5CCR8HDAC6METAP2
SCHEMBL14804379 0.89 CCR1 (0.89) CCR1CCR5CCR8HDAC6METAP2
SCHEMBL10000248 0.86 CCR1 (0.68) CCR1CCR5CCR8HDAC6METAP2
SCHEMBL17051514 0.86 CCR1 (0.75) CCR1CCR5CCR8HDAC6METAP2
SCHEMBL17051522 0.84 CCR1 (0.65) CCR1CCR5CCR8HDAC6METAP2
SCHEMBL14804374 0.84 CCR1 (0.73) CCR1CCR5CCR8HDAC6METAP2
Abametapir SCHEMBL351152 0.83 CCR1 (1.00) CCR1CCR5CCR8HDAC6METAP2
Abametapir SCHEMBL29374261 0.83 CCR1 (1.00) CCR1CCR5CCR8HDAC6METAP2
SCHEMBL17051525 0.83 CCR1 (0.58) CCR1CCR5CCR8HDAC6METAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8981354-B2 Organic light-emitting polymer and device CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2015-03-17 US disclosed
US-8981354-B2 Organic light-emitting polymer and device CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2015-03-17 US disclosed
US-20130299787-A1 ORGANIC LIGHT-EMITTING DEVICE AND METHOD SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2013-11-14 US disclosed
US-20130299787-A1 ORGANIC LIGHT-EMITTING DEVICE AND METHOD SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2013-11-14 US disclosed
US-20130146852-A1 ORGANIC LIGHT-EMITTING POLYMER AND DEVICE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2013-06-13 US disclosed
US-20130146852-A1 ORGANIC LIGHT-EMITTING POLYMER AND DEVICE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2013-06-13 US disclosed
US-20130075714-A1 POLYMER, POLYMER COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE SUMTOMO CHEMICAL COMPANY LIMITED (JP) 2013-03-28 US disclosed
US-20130075714-A1 POLYMER, POLYMER COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE SUMTOMO CHEMICAL COMPANY LIMITED (JP) 2013-03-28 US disclosed
WO-2012052713-A1 ORGANIC LIGHT-EMITTING DEVICE AND METHOD CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2012-04-26 WO disclosed