Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.64 |
| ▸ | RARB | P10826 | 3/20 | 0.61 |
| ▸ | PPARG | P37231 | 2/20 | 0.61 |
| ▸ | PPARA | Q07869 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | PLK1 | P53350 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19781425 | 1.00 | MMP1 (0.68) | MMP1TP53TSHRPLA2G4BRARB | |
| SCHEMBL12894669 | 0.96 | MMP1 (0.74) | MMP1TP53TSHRALDH1A1LMNA | |
| SCHEMBL835053 | 0.90 | PLK1 (0.67) | MMP1TSHRALDH1A1LMNAMEN1 | |
| SCHEMBL8947303 | 0.87 | MMP1 (0.67) | MMP1TP53TSHRPLA2G4BRARB | |
| SCHEMBL28570651 | 0.87 | NPC1 (0.68) | MMP1TP53TSHRPLA2G4BALDH1A1 | |
| SCHEMBL12638372 | 0.86 | MMP1 (0.65) | MMP1TP53TSHRPLA2G4BPOLB | |
| SCHEMBL9402561 | 0.86 | PLA2G2A (0.66) | MMP1TP53TSHRPLA2G4BALDH1A1 | |
| SCHEMBL9402758 | 0.86 | PLA2G2A (0.66) | MMP1TP53TSHRPLA2G4BALDH1A1 | |
| SCHEMBL11758823 | 0.85 | NPC1 (0.72) | MMP1TP53TSHRPLA2G4BMEN1 | |
| SCHEMBL9490019 | 0.85 | NPC1 (0.72) | MMP1TP53TSHRPLA2G4BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7868135-B2 | Compositions of lipopeptide antibiotic derivatives and methods of use thereof | BIOWEST THERAPEUTICS INC. (CA) | 2011-01-11 | — | — | US | disclosed |