SCHEMBL10000286

SCHEMBL10000286

Cc1ccc(NC(=O)c2ccc3c(c2)CN(C)C3)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 11/20 0.59
NPC1 O15118 9/20 0.59
TMPRSS2 O15393 1/20 0.55
SMN1; SMN2 Q16637 5/20 0.55
MAPT P10636 4/20 0.55
ALDH1A1 P00352 1/20 0.55
NFKB1 P19838 1/20 0.55
NFKB2 Q00653 1/20 0.55
RELA Q04206 1/20 0.55
HPGD P15428 1/20 0.53
NAMPT P43490 3/20 0.52
TAS1R3 Q7RTX0 1/20 0.51
TAS1R1 Q7RTX1 1/20 0.51
TAS1R2 Q8TE23 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
LMNA P02545 2/20 0.51
KDM4E B2RXH2 1/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
MCL1 Q07820 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10000285 0.92 RAB9A (0.52) RAB9ANPC1TMPRSS2SMN1; SMN2MAPT
SCHEMBL6295061 0.82 RAB9A (0.69) RAB9ANPC1TMPRSS2SMN1; SMN2MAPT
SCHEMBL7306324 0.79 NPC1 (0.78) RAB9ANPC1TMPRSS2SMN1; SMN2MAPT
SCHEMBL26075332 0.77 HDAC6 (0.50) NAMPT
SCHEMBL14580374 0.76 RAB9A (1.00) RAB9ANPC1SMN1; SMN2MAPTALDH1A1
SCHEMBL12310125 0.76 RAB9A (1.00) RAB9ANPC1SMN1; SMN2MAPTALDH1A1
SCHEMBL15214321 0.76 RAB9A (1.00) RAB9ANPC1SMN1; SMN2MAPTALDH1A1
SCHEMBL822378 0.76 RAB9A (1.00) RAB9ANPC1SMN1; SMN2MAPTALDH1A1
SCHEMBL27181403 0.76 RAB9A (1.00) RAB9ANPC1SMN1; SMN2MAPTALDH1A1
SCHEMBL12082773 0.74 RAB9A (1.00) RAB9ANPC1SMN1; SMN2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160367935-A1 DEFECT-FREE CARBON MOLECULAR SIEVE MEMBRANES WITH ENHANCED SELECTIVITY AND AGING RESISTANCE AND THE METHOD OF MAKING THE SAME L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude (FR) 2016-12-22 US disclosed
US-20160151746-A1 COMPOSITE CARBON MOLECULAR SIEVE MEMBRANES HAVING ANTI-SUBSTRUCTURE COLLAPSE PARTICLES LOADED IN A CORE THEREOF AMERICAN AIR LIQUIDE, INC. 2016-06-02 US disclosed
US-8101009-B2 Separation membrane by controlled annealing of polyimide polymers L'AIR LIQUIDE SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2012-01-24 US disclosed
US-20090227744-A1 Separation Membrane by Controlled Annealing of Polyimide Polymers L'AIR LIQUIDE SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2009-09-10 US disclosed