SCHEMBL10000330

SCHEMBL10000330

O=C(COCCO)ON1C(=O)CCC1=O

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA2B P29275 1/20 0.32
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL803306 0.94
2-Methoxyethanol SCHEMBL31177228 0.92 HPGD (0.33) ADORA3ADORA2AADORA2B
SCHEMBL12743131 0.91 ADORA3 (0.33) ADORA3ADORA2AADORA2B
SCHEMBL15503042 0.90 ALOX12 (0.31) ADORA3ADORA2AADORA2B
SCHEMBL24621700 0.89 ADORA3 (0.33) ADORA3ADORA2AADORA2B
SCHEMBL17167184 0.89 ADORA3 (0.33) ADORA3ADORA2AADORA2B
SCHEMBL2568708 0.87 ADORA3 (0.37) ADORA3ADORA2AADORA2B
SCHEMBL16303082 0.86 ADORA3 (0.32) ADORA3ADORA2AADORA2B
SCHEMBL29713990 0.85 PSMB8 (0.31)
SCHEMBL3521348 0.84 TSHR (0.34) TSHRMAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115919755-A Low-concentration hydrogel and preparation method and application thereof 沈阳药科大学 2023-04-07 CN claimed
CN-115819550-A Interleukin-2 mutant and polyethylene glycol modifier and preparation method thereof 江苏众红生物工程创药研究院有限公司 2023-03-21 CN claimed
CN-110251731-B Islet cell microcapsule for tissue engineering and preparation method thereof 山东百多安医疗器械股份有限公司 2021-09-03 CN claimed
CN-110201234-B Prostate cell microcapsule for tissue engineering and preparation method thereof 山东百多安医疗器械股份有限公司 2021-09-03 CN claimed
CN-104693433-B A kind of Pegylation Amifostine, preparation method and its usage 国家纳米科学中心 2017-06-06 CN claimed
CN-118344617-A Bioactive hydrogel and preparation method and application thereof 香港中文大学 2024-07-16 CN disclosed
CN-117731826-A Platelet-rich plasma hydrogel with growth factors slowly released and preparation method and application thereof 武汉理工大学 2024-03-22 CN disclosed
CN-115919755-A Low-concentration hydrogel and preparation method and application thereof 沈阳药科大学 2023-04-07 CN disclosed
CN-115869456-A Preparation of in-situ gelation anti-swelling enhanced tissue adhesive material 上海其胜生物制剂有限公司 2023-03-31 CN disclosed
CN-115819550-A Interleukin-2 mutant and polyethylene glycol modifier and preparation method thereof 江苏众红生物工程创药研究院有限公司 2023-03-21 CN disclosed
CN-114306722-B Injectable hydrogel type biological adhesive and preparation and application thereof 华东理工大学 2022-12-30 CN disclosed
CN-114306722-A Injectable hydrogel type biological adhesive and preparation and application thereof 华东理工大学 2022-04-12 CN disclosed
US-20140044672-A1 CONJUGATES OF A GM-CSF MOIETY AND A POLYMER NEKTAR THERAPEUTICS (US) 2014-02-13 US disclosed
US-8470891-B2 Biodegradable block polymers for drug delivery, and methods related thereto INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-06-25 US disclosed
US-8470891-B2 Biodegradable block polymers for drug delivery, and methods related thereto INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-06-25 US disclosed
US-20120322737-A1 MODIFIED RECOMBINANT FACTOR VIII AND VON WILLEBRAND FACTOR AND METHODS OF USE BAXTER HEALTHCARE S.A. (CH) 2012-12-20 US disclosed
US-20120083767-A1 IMPLANTABLE BIOREACTOR FOR DELIVERY OF PARACRINE FACTORS THE JOHNS HOPKINS UNIVERSITY (US) 2012-04-05 US disclosed
US-20110152167-A1 BIODEGRADABLE BLOCK POLYMERS FOR DRUG DELIVERY, AND METHODS RELATED THERETO AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-06-23 US disclosed
US-20110152167-A1 BIODEGRADABLE BLOCK POLYMERS FOR DRUG DELIVERY, AND METHODS RELATED THERETO AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-06-23 US disclosed
WO-2010117460-A1 SURFACE MODIFICATION OF REVERSE OSMOSIS MEMBRANES BY HYDROPHILIC DENDRITIC POLYMERS MICHIGAN MOLECULAR INSTITUTE (US) 2010-10-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120322737-A1 MODIFIED RECOMBINANT FACTOR VIII AND VON WILLEBRAND FACTOR AND METHODS OF USE F8, F5, F13B ADORA3 2154/4885ADORA2A 1684/4885ADORA2B 1180/4885
US-20140044672-A1 CONJUGATES OF A GM-CSF MOIETY AND A POLYMER CSF3R, GMFG, CSF1R ADORA3 4241/4885ADORA2A 4299/4885ADORA2B 4596/4885
US-20110152167-A1 BIODEGRADABLE BLOCK POLYMERS FOR DRUG DELIVERY, AND METHODS RELATED THERETO SAMM50, ADRM1, UFM1 ADORA3 2115/4885ADORA2A 2587/4885ADORA2B 831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.