SCHEMBL10000408

SCHEMBL10000408

COC(=O)C(Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)NC(=O)COCC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 9/20 0.43
▸ MEN1 O00255 7/20 0.43
▸ KMT2A Q03164 7/20 0.43
▸ THRA P10827 6/20 0.43
▸ LMNA P02545 6/20 0.43
▸ PPARG P37231 5/20 0.43
▸ HSD17B10 Q99714 3/20 0.43
▸ ALDH1A1 P00352 3/20 0.43
▸ USP2 O75604 3/20 0.43
▸ TTR P02766 2/20 0.43
▸ ADORA3 P0DMS8 2/20 0.43
▸ PDE4D Q08499 2/20 0.43
▸ RXRA P19793 2/20 0.43
▸ MAPT P10636 2/20 0.43
▸ NR3C1 P04150 1/20 0.43
▸ CYP1A2 P05177 1/20 0.43
▸ HTR1A P08908 1/20 0.43
▸ CYP2C9 P11712 1/20 0.43
▸ TBXA2R P21731 1/20 0.43
▸ NTSR1 P30989 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27293656 0.83 THRB (0.52) THRBMEN1KMT2ATHRALMNA
SCHEMBL27293659 0.83 THRB (0.52) THRBMEN1KMT2ATHRALMNA
SCHEMBL8371976 0.83 THRB (0.56) THRBMEN1KMT2ATHRALMNA
SCHEMBL10000410 0.83 THRB (0.51) THRBMEN1KMT2ATHRALMNA
SCHEMBL8371977 0.83 THRB (0.56) THRBMEN1KMT2ATHRALMNA
SCHEMBL8370895 0.80 THRB (0.47) THRBMEN1KMT2ATHRALMNA
SCHEMBL8370896 0.80 THRB (0.47) THRBMEN1KMT2ATHRALMNA
SCHEMBL8372964 0.79 THRB (0.40) THRBMEN1KMT2ATHRALMNA
SCHEMBL8370753 0.79 THRB (0.43) THRBMEN1KMT2ATHRALMNA
SCHEMBL8370758 0.79 THRB (0.43) THRBMEN1KMT2ATHRALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8912010-B2 Thyroxine immunoassay using fluorescent particles FUJIFILM CORPORATION (JP) 2014-12-16 — — US disclosed
US-8912010-B2 Thyroxine immunoassay using fluorescent particles FUJIFILM CORPORATION (JP) 2014-12-16 — — US disclosed
US-8524864-B2 Method for producing conjugate of thyroxine and albumin FUJIFILM CORPORATION (JP) 2013-09-03 — — US disclosed
US-8524864-B2 Method for producing conjugate of thyroxine and albumin FUJIFILM CORPORATION (JP) 2013-09-03 — — US disclosed
US-20130078737-A1 THYROXINE IMMUNOASSAY USING FLUORESCENT PARTICLES FUJIFILM CORPORATION (JP) 2013-03-28 — — US disclosed
US-20130078737-A1 THYROXINE IMMUNOASSAY USING FLUORESCENT PARTICLES FUJIFILM CORPORATION (JP) 2013-03-28 — — US disclosed
US-20120046447-A1 METHOD FOR PRODUCING CONJUGATE OF THYROXINE AND ALBUMIN FUJIFILM CORPORATION (JP) 2012-02-23 — — US disclosed
US-20120046447-A1 METHOD FOR PRODUCING CONJUGATE OF THYROXINE AND ALBUMIN FUJIFILM CORPORATION (JP) 2012-02-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120046447-A1 METHOD FOR PRODUCING CONJUGATE OF THYROXINE AND ALBUMIN ALB, TPO, TTR THRB 9/4885MEN1 1798/4885KMT2A 3342/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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