SCHEMBL10000555

SCHEMBL10000555

Cc1ccccc1-c1ncc2ccccc2c1C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.45
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 2/20 0.45
HPGD P15428 2/20 0.45
MEN1 O00255 1/20 0.45
CYP1A2 P05177 1/20 0.45
GLA P06280 1/20 0.45
CYP2C19 P33261 1/20 0.45
HSD17B10 Q99714 1/20 0.45
ADORA2A P29274 1/20 0.43
CSNK2A2 P19784 1/20 0.43
CSNK2B P67870 1/20 0.43
PDE10A Q9Y233 2/20 0.42
TSHR P16473 1/20 0.42
SMO Q99835 1/20 0.41
DHODH Q02127 6/20 0.40
GAA P10253 1/20 0.39
LDHA P00338 1/20 0.39
NPC1 O15118 1/20 0.38
NR1H4 Q96RI1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10000567 0.83 PDE10A (0.43) KMT2AKDM4EALDH1A1HPGDMEN1
SCHEMBL10028037 0.82 NPC1 (0.50) KMT2AKDM4EALDH1A1HPGDMEN1
SCHEMBL14407613 0.78 ADORA2A (0.46) KDM4EALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL10027991 0.77 CTSD (0.42) KMT2AKDM4EALDH1A1HPGDMEN1
SCHEMBL10781354 0.76 MYC (0.50) KMT2AKDM4EALDH1A1HPGDCYP1A2
SCHEMBL10778674 0.75 KMT2A (0.52) KMT2AALDH1A1HPGDCYP2C19ADORA2A
SCHEMBL10000590 0.73 MCL1 (0.53) KMT2AKDM4EALDH1A1HPGDMEN1
SCHEMBL28050965 0.73 KDM4E (0.55) KMT2AKDM4EALDH1A1HPGDMEN1
SCHEMBL4360503 0.72 ADORA2A (0.56) KMT2AKDM4EALDH1A1CYP2C19HSD17B10
SCHEMBL10000554 0.72 LMNA (0.48) KDM4EALDH1A1CYP1A2CYP2C19ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150340628-A1 METAL COMPLEX COMPOUND AND ORGANIC LIGHT EMITTING DIODE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2015-11-26 US disclosed
US-9096529-B2 Metal complex compound and organic light emitting diode device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-08-04 US disclosed
US-20120012824-A1 METAL COMPLEX COMPOUND AND ORGANIC LIGHT EMITTING DIODE DEVICE INCLUDING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150340628-A1 METAL COMPLEX COMPOUND AND ORGANIC LIGHT EMITTING DIODE DEVICE INCLUDING THE SAME AP1M1, MT-CO1, AP2M1 KMT2A 1392/4885KDM4E 3600/4885ALDH1A1 122/4885
US-20120012824-A1 METAL COMPLEX COMPOUND AND ORGANIC LIGHT EMITTING DIODE DEVICE INCLUDING THE SAME AP1M1, MT-CO1, AP2M1 KMT2A 1392/4885KDM4E 3600/4885ALDH1A1 122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.