SCHEMBL10000560

SCHEMBL10000560

Cc1c2c(cc3ccccc13)Cc1cccnc1-2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 2/20 0.37
CCR8 P51685 2/20 0.37
NPC1 O15118 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
HSP90AA1 P07900 1/20 0.36
CYP3A4 P08684 2/20 0.36
TSHR P16473 2/20 0.36
KDM4E B2RXH2 2/20 0.36
MEN1 O00255 1/20 0.36
TP53 P04637 1/20 0.36
CYP2D6 P10635 1/20 0.36
MAPT P10636 1/20 0.36
CYP2C9 P11712 1/20 0.36
PKM P14618 1/20 0.36
MAPK1 P28482 1/20 0.36
CYP2C19 P33261 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10000598 0.86 CYP2A6 (0.39) NPC1L3MBTL1HSP90AA1KDM4ECYP2A6
SCHEMBL10027757 0.82 KDM4E (0.39) NPC1CYP3A4TSHRKDM4EMEN1
SCHEMBL10000577 0.78 PDGFRB (0.39) NPC1CYP3A4TSHRKDM4EMEN1
SCHEMBL10000565 0.78 CYP2A6 (0.36) TSHRKDM4ECYP2A6CYP1A2
SCHEMBL10000572 0.78 MAPT (0.54) NPC1CYP3A4TSHRKDM4EMEN1
SCHEMBL25983059 0.73 CYP2A6 (0.39) NPC1L3MBTL1HSP90AA1CYP3A4CYP2D6
SCHEMBL10028264 0.70 MAOA (0.48) CYP3A4TSHRKDM4ETP53CYP2D6
SCHEMBL10000562 0.70 PDK2 (0.39) CCR1CCR8NPC1L3MBTL1HSP90AA1
SCHEMBL10000558 0.70 GAA (0.50) CCR1CCR8L3MBTL1MEN1MAPT
SCHEMBL10000546 0.69 CYP2A6 (0.44) NPC1L3MBTL1CYP3A4TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150340628-A1 METAL COMPLEX COMPOUND AND ORGANIC LIGHT EMITTING DIODE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2015-11-26 US disclosed
US-9096529-B2 Metal complex compound and organic light emitting diode device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-08-04 US disclosed
US-20120012824-A1 METAL COMPLEX COMPOUND AND ORGANIC LIGHT EMITTING DIODE DEVICE INCLUDING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150340628-A1 METAL COMPLEX COMPOUND AND ORGANIC LIGHT EMITTING DIODE DEVICE INCLUDING THE SAME AP1M1, MT-CO1, AP2M1 CCR1 1451/4885CCR8 3158/4885NPC1 1702/4885
US-20120012824-A1 METAL COMPLEX COMPOUND AND ORGANIC LIGHT EMITTING DIODE DEVICE INCLUDING THE SAME AP1M1, MT-CO1, AP2M1 CCR1 1451/4885CCR8 3158/4885NPC1 1702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.