SCHEMBL10000574

SCHEMBL10000574

Cc1c(-c2nc3ccccc3cc2C(=O)O)ccc2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.46
TSHR P16473 2/20 0.46
PDE10A Q9Y233 3/20 0.46
DHODH Q02127 1/20 0.44
KDM4E B2RXH2 3/20 0.43
ALDH1A1 P00352 3/20 0.43
HPGD P15428 2/20 0.43
WDR5 P61964 1/20 0.43
LDHA P00338 1/20 0.42
LMNA P02545 2/20 0.42
NR4A1 P22736 1/20 0.41
NR4A2 P43354 1/20 0.41
NR4A3 Q92570 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16975588 0.83 KDM4E (0.46) NPC1RAB9AKMT2AMEN1SMN1; SMN2
SCHEMBL8807038 0.79 SMN1; SMN2 (0.56) NPC1RAB9AKMT2AMEN1SMN1; SMN2
SCHEMBL10000579 0.78 CAMKK2 (0.43) KMT2AMEN1SMN1; SMN2TSHRPDE10A
SCHEMBL10000561 0.77 KDM4E (0.54) SMN1; SMN2TSHRDHODHKDM4EALDH1A1
SCHEMBL3912410 0.75 PDE10A (0.56) NPC1RAB9AKMT2AMEN1SMN1; SMN2
SCHEMBL10512169 0.74 SMN1; SMN2 (0.44) NPC1RAB9AKMT2AMEN1SMN1; SMN2
SCHEMBL10000569 0.74 PDE4B (0.50) KMT2AMEN1SMN1; SMN2TSHRPDE10A
SCHEMBL8521039 0.74 NPC1 (0.63) NPC1RAB9AKMT2AMEN1SMN1; SMN2
SCHEMBL30251636 0.73 ALDH1A1 (0.67) NPC1RAB9AKMT2AMEN1SMN1; SMN2
SCHEMBL4302924 0.73 ALDH1A1 (0.67) NPC1RAB9AKMT2AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150340628-A1 METAL COMPLEX COMPOUND AND ORGANIC LIGHT EMITTING DIODE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2015-11-26 US disclosed
US-9096529-B2 Metal complex compound and organic light emitting diode device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-08-04 US disclosed
US-20120012824-A1 METAL COMPLEX COMPOUND AND ORGANIC LIGHT EMITTING DIODE DEVICE INCLUDING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150340628-A1 METAL COMPLEX COMPOUND AND ORGANIC LIGHT EMITTING DIODE DEVICE INCLUDING THE SAME AP1M1, MT-CO1, AP2M1 NPC1 1702/4885RAB9A 720/4885KMT2A 1392/4885
US-20120012824-A1 METAL COMPLEX COMPOUND AND ORGANIC LIGHT EMITTING DIODE DEVICE INCLUDING THE SAME AP1M1, MT-CO1, AP2M1 NPC1 1702/4885RAB9A 720/4885KMT2A 1392/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.