SCHEMBL10000580

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10000576	0.86	PSMB5 (0.36)	KDM4EIDO1TDO2CTDSP1TDP1
	SCHEMBL10028258	0.83	IDO1 (0.41)	IDO1TDO2CTDSP1TDP1ALDH1A1
	SCHEMBL10000559	0.79	PDK2 (0.38)	KDM4ETDP1MEN1ALDH1A1MAPT
	SCHEMBL10000568	0.78	NQO1 (0.35)	KDM4EIDO1TDO2MEN1KMT2A
	SCHEMBL10000570	0.78	KMT2A (0.43)	KDM4ETDP1MEN1ALDH1A1MAPT
	SCHEMBL22910049	0.73	MEN1 (0.44)	KDM4EMEN1ALDH1A1MAPTHPGD
	SCHEMBL10000594	0.71	CA12 (0.38)	KDM4EIDO1TDO2MEN1MAPT
	SCHEMBL80941	0.69	PDK2 (0.45)	KDM4ETDP1MEN1ALDH1A1MAPT
	SCHEMBL10000597	0.68	PDK2 (0.36)	KDM4EMAPTKMT2APDK2
	SCHEMBL21577060	0.68	PDK2 (0.33)	IDO1TDO2MEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.