SCHEMBL10000597

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10000599	0.87	PDK2 (0.37)	PDK2KDM4EHTTPOLBRAD52
	SCHEMBL10000559	0.85	PDK2 (0.38)	PDK2KDM4EHTTMAPTCYP1A2
	SCHEMBL10028266	0.82	MAOA (0.47)	PDK2KDM4EHTTPOLBRAD52
	SCHEMBL10000562	0.73	PDK2 (0.39)	PDK2KDM4EPOLBCYP2A6MAPT
	SCHEMBL10000618	0.71	PDK2 (0.38)	PDK2KDM4ECYP2A6CYP1A2CYP2C19
	SCHEMBL10027758	0.70	KDM4E (0.35)	PDK2KDM4EPOLB
	SCHEMBL26710546	0.69	TNF (0.33)	PDK2CYP1A2CYP2C19KMT2A
	SCHEMBL10000545	0.68	PDK2 (0.44)	PDK2KDM4EHTTMAPTCYP1A2
	SCHEMBL10000580	0.68	KDM4E (0.39)	PDK2KDM4EMAPTKMT2A
	SCHEMBL1335900	0.68	PDK2 (0.43)	PDK2KDM4EPOLBCYP2A6MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.