SCHEMBL10028258

SCHEMBL10028258

COc1c2c(cc3ccccc13)C(C)(C)c1cc(-c3ccccc3)cnc1-2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.41
TDO2 P48775 2/20 0.41
CTDSP1 Q9GZU7 2/20 0.40
PDGFRB P09619 2/20 0.39
PDGFRA P16234 1/20 0.39
FYN P06241 1/20 0.38
MAPT P10636 2/20 0.37
CASP1 P29466 1/20 0.37
ALOX5AP P20292 1/20 0.37
FEN1 P39748 1/20 0.37
DHODH Q02127 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
LMNA P02545 1/20 0.35
HPGD P15428 1/20 0.35
POLB P06746 1/20 0.34
MAP3K11 Q16584 2/20 0.34
KDR P35968 2/20 0.34
ALDH1A1 P00352 2/20 0.33
GAA P10253 2/20 0.33
GLA P06280 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10000576 0.84 PSMB5 (0.36) IDO1TDO2CTDSP1PDGFRBPDGFRA
SCHEMBL10000580 0.83 KDM4E (0.39) IDO1TDO2CTDSP1PDGFRBPDGFRA
SCHEMBL10027758 0.80 KDM4E (0.35) PDGFRBPDGFRASMN1; SMN2HPGDPOLB
SCHEMBL10027989 0.79 CTDSP1 (0.38) IDO1TDO2CTDSP1SMN1; SMN2HPGD
SCHEMBL10028051 0.79 POLB (0.41) MAPTSMN1; SMN2HPGDPOLBALDH1A1
SCHEMBL10028260 0.75 CTDSP1 (0.41) IDO1TDO2CTDSP1PDGFRBPDGFRA
SCHEMBL10028256 0.74 FYN (0.43) IDO1TDO2CTDSP1PDGFRBPDGFRA
SCHEMBL22910049 0.71 MEN1 (0.44) PDGFRBPDGFRAMAPTCASP1SMN1; SMN2
SCHEMBL10028266 0.70 MAOA (0.47) IDO1TDO2MAPTPOLB
SCHEMBL10027999 0.70 PDGFRB (0.41) PDGFRBPDGFRAMAPTALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150340628-A1 METAL COMPLEX COMPOUND AND ORGANIC LIGHT EMITTING DIODE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2015-11-26 US disclosed
US-9096529-B2 Metal complex compound and organic light emitting diode device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-08-04 US disclosed
US-20120012824-A1 METAL COMPLEX COMPOUND AND ORGANIC LIGHT EMITTING DIODE DEVICE INCLUDING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150340628-A1 METAL COMPLEX COMPOUND AND ORGANIC LIGHT EMITTING DIODE DEVICE INCLUDING THE SAME AP1M1, MT-CO1, AP2M1 IDO1 2635/4885TDO2 2079/4885CTDSP1 3421/4885
US-20120012824-A1 METAL COMPLEX COMPOUND AND ORGANIC LIGHT EMITTING DIODE DEVICE INCLUDING THE SAME AP1M1, MT-CO1, AP2M1 IDO1 2635/4885TDO2 2079/4885CTDSP1 3421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.