SCHEMBL10000620

SCHEMBL10000620

Cc1cncc2c1-c1ncccc1C2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.45
CNR2 P34972 1/20 0.35
METAP2 P50579 1/20 0.35
NOS3 P29474 1/20 0.32
NOS1 P29475 1/20 0.32
NOS2 P35228 1/20 0.32
NPC1 O15118 1/20 0.32
HSP90AA1 P07900 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PDK2 Q15119 1/20 0.31
CHRM2 P08172 1/20 0.31
HTR1A P08908 1/20 0.31
CHRM1 P11229 1/20 0.31
DRD2 P14416 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
ADRA1A P35348 1/20 0.31
HRH1 P35367 1/20 0.31
OPRK1 P41145 1/20 0.31
HTR2B P41595 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10000546 0.81 CYP2A6 (0.44) CYP2A6CNR2METAP2NOS3NOS1
SCHEMBL10028268 0.80 CYP19A1 (0.36) CYP2A6HTR1A
SCHEMBL25983059 0.75 CYP2A6 (0.39) CYP2A6CNR2METAP2NOS3NOS1
SCHEMBL577689 0.73 TDP1 (0.42) CYP2A6HSP90AA1CHRM2HTR1ACHRM1
SCHEMBL17264307 0.72 GABRG2 (0.41) CYP2A6
SCHEMBL12319813 0.70 NOS3 (0.44) CYP2A6CNR2METAP2NOS3NOS1
SCHEMBL9261195 0.70 CYP2A6 (0.41) CYP2A6PTGS2
SCHEMBL26221034 0.70 CYP2A6 (0.41) CYP2A6CNR2PDK2CHRM2HTR1A
SCHEMBL10000598 0.70 CYP2A6 (0.39) CYP2A6NPC1HSP90AA1L3MBTL1HRH1
SCHEMBL25983070 0.69 CYP2A6 (0.40) CYP2A6CNR2METAP2NOS3NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150340628-A1 METAL COMPLEX COMPOUND AND ORGANIC LIGHT EMITTING DIODE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2015-11-26 US disclosed
US-9096529-B2 Metal complex compound and organic light emitting diode device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-08-04 US disclosed
US-20120012824-A1 METAL COMPLEX COMPOUND AND ORGANIC LIGHT EMITTING DIODE DEVICE INCLUDING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150340628-A1 METAL COMPLEX COMPOUND AND ORGANIC LIGHT EMITTING DIODE DEVICE INCLUDING THE SAME AP1M1, MT-CO1, AP2M1 CYP2A6 501/4885CNR2 3357/4885METAP2 2575/4885
US-20120012824-A1 METAL COMPLEX COMPOUND AND ORGANIC LIGHT EMITTING DIODE DEVICE INCLUDING THE SAME AP1M1, MT-CO1, AP2M1 CYP2A6 501/4885CNR2 3357/4885METAP2 2575/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.