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SCHEMBL10000644

SCHEMBL10000644

Cc1cc(C)c(C(C)(C)C)cc1Sc1cc(C(C)(C)C)c(O)cc1C

nearest known ligand 0.89

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX15 P16050 8/20 0.89
▸ ALDH1A1 P00352 7/20 0.89
▸ SMN1; SMN2 Q16637 4/20 0.89
▸ TP53 P04637 4/20 0.89
▸ HIF1A Q16665 4/20 0.89
▸ CYP3A4 P08684 3/20 0.89
▸ TSHR P16473 2/20 0.89
▸ TDP1 Q9NUW8 2/20 0.89
▸ MAPK1 P28482 2/20 0.89
▸ MAPT P10636 4/20 0.50
▸ CYP1A2 P05177 3/20 0.50
▸ KDM4E B2RXH2 2/20 0.50
▸ ATP2A2 P16615 1/20 0.50
▸ ATP2A3 Q93084 1/20 0.50
▸ CYP2C9 P11712 6/20 0.42
▸ CYP2C19 P33261 5/20 0.42
▸ CYP2D6 P10635 3/20 0.42
▸ LMNA P02545 3/20 0.39
▸ HPGD P15428 3/20 0.39
▸ HSD17B10 Q99714 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29366086 0.94 ALOX15 (1.00) ALOX15ALDH1A1SMN1; SMN2TP53HIF1A
SCHEMBL39505 0.94 ALOX15 (1.00) ALOX15ALDH1A1SMN1; SMN2TP53HIF1A
SCHEMBL31295681 0.94 ALOX15 (1.00) ALOX15ALDH1A1SMN1; SMN2TP53HIF1A
Formaldehyde SCHEMBL8818886 0.89 ALOX15 (0.89) ALOX15ALDH1A1SMN1; SMN2TP53HIF1A
SCHEMBL9668266 0.89 ALOX15 (0.89) ALOX15ALDH1A1SMN1; SMN2TP53HIF1A
SCHEMBL12626233 0.89 ALOX15 (0.89) ALOX15ALDH1A1SMN1; SMN2TP53HIF1A
SCHEMBL3663625 0.89 ALOX15 (0.89) ALOX15ALDH1A1SMN1; SMN2TP53HIF1A
SCHEMBL17826417 0.88 ALDH1A1 (0.67) ALOX15ALDH1A1SMN1; SMN2TP53HIF1A
Bicarbonate SCHEMBL11447857 0.87 ALOX15 (0.86) ALOX15ALDH1A1SMN1; SMN2TP53HIF1A
SCHEMBL10039800 0.86 ALOX15 (0.85) ALOX15ALDH1A1SMN1; SMN2TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11827829-B2 Liquid crystal composition containing dibenzo derivative and liquid crystal display device JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-11-28 — — US disclosed
US-11787978-B2 Product assembly adhesives comprising low volatile tackifier compositions SYNTHOMER ADHESIVE TECHNOLOGIES LLC (US) 2023-10-17 — — US disclosed
US-11753566-B2 Low volatile tackifier compositions SYNTHOMER ADHESIVE TECHNOLOGIES LLC (US) 2023-09-12 — — US disclosed
US-11725122-B2 Processes for making low volatile tackifier compositions SYNTHOMER ADHESIVE TECHNOLOGIES LLC (US) 2023-08-15 — — US disclosed
WO-2020193563-A1 METHOD FOR STABILIZING THERMOPLASTIC RECYCLATES, STABILIZED PLASTIC COMPOSITIONS, AND MOLDING COMPOUNDS AND MOLDED PARTS PRODUCED THEREFROM Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2020-10-01 — — WO disclosed
US-20180201798-A1 AQUEOUS INKJET INKS AGFA-GEVAERT (BE) 2018-07-19 — — US disclosed
US-20180148612-A1 STABILIZATION OF HOT MELT ADHESIVES BASF SE (DE) 2018-05-31 — — US disclosed
US-8217105-B2 Stabilized medium and high voltage insulation composition BASF SE (DE) 2012-07-10 — — US disclosed
US-8093320-B2 Compositions comprising polyphosphonates and additives that exhibit an advantageous combination of properties, and methods related thereto FRX POLYMERS, INC. (US) 2012-01-10 — — US disclosed
US-20100036031-A1 STABILIZED MEDIUM AND HIGH VOLTAGE INSULATION COMPOSITION CIBA CORPORATION 2010-02-11 — — US disclosed