SCHEMBL3663625

SCHEMBL3663625

Cc1cc(O)c(C(C)(C)C)cc1Sc1cc(C(C)(C)C)c(O)cc1C.Cc1cc(O)c(C(C)(C)C)cc1Sc1cc(C(C)(C)C)c(O)cc1C.Cc1cc(O)c(C(C)(C)C)cc1Sc1cc(C(C)(C)C)c(O)cc1C.OP(O)O

nearest known ligand 0.89

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 8/20 0.89
ALDH1A1 P00352 8/20 0.89
TP53 P04637 4/20 0.89
SMN1; SMN2 Q16637 3/20 0.89
CYP3A4 P08684 3/20 0.89
TDP1 Q9NUW8 3/20 0.89
HIF1A Q16665 3/20 0.89
TSHR P16473 2/20 0.89
MAPK1 P28482 2/20 0.89
MAPT P10636 4/20 0.50
CYP1A2 P05177 3/20 0.50
KDM4E B2RXH2 2/20 0.50
ATP2A2 P16615 1/20 0.50
ATP2A3 Q93084 1/20 0.50
CYP2C9 P11712 5/20 0.42
CYP2C19 P33261 4/20 0.42
CYP2D6 P10635 3/20 0.42
LMNA P02545 3/20 0.39
HPGD P15428 3/20 0.39
HSD17B10 Q99714 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9668266 1.00 ALOX15 (0.89) ALOX15ALDH1A1TP53SMN1; SMN2CYP3A4
SCHEMBL31295681 0.94 ALOX15 (1.00) ALOX15ALDH1A1TP53SMN1; SMN2CYP3A4
SCHEMBL39505 0.94 ALOX15 (1.00) ALOX15ALDH1A1TP53SMN1; SMN2CYP3A4
SCHEMBL29366086 0.94 ALOX15 (1.00) ALOX15ALDH1A1TP53SMN1; SMN2CYP3A4
Formaldehyde SCHEMBL8818886 0.89 ALOX15 (0.89) ALOX15ALDH1A1TP53SMN1; SMN2CYP3A4
SCHEMBL12626233 0.89 ALOX15 (0.89) ALOX15ALDH1A1TP53SMN1; SMN2CYP3A4
SCHEMBL10000644 0.89 ALOX15 (0.89) ALOX15ALDH1A1TP53SMN1; SMN2CYP3A4
Bicarbonate SCHEMBL11447857 0.87 ALOX15 (0.86) ALOX15ALDH1A1TP53SMN1; SMN2CYP3A4
SCHEMBL10039800 0.86 ALOX15 (0.85) ALOX15ALDH1A1TP53SMN1; SMN2CYP3A4
SCHEMBL9008249 0.85 ALOX15 (0.69) ALOX15ALDH1A1TP53SMN1; SMN2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8350058-B2 Reaction of maleic acid, maleic anhydride, fumaric acid and an alkene which contains 4-250 carbon atoms at from 150 to 250 degrees C. in the presence of a synergistic mixture of a primary antioxidant, a secondary antioxidant, and a metal deactivator CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2013-01-08 US claimed
EP-1828157-B1 METHOD FOR PRODUCING ALKENYL SUCCINIC ANHYDRIDES CLARIANT PRODUKTE DEUTSCHLAND (DE) 2010-03-03 EP claimed
US-20080108836-A1 Method For Producing Alkenyl Succinic Anhydrides CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2008-05-08 US claimed
EP-1828157-A1 METHOD FOR PRODUCING ALKENYL SUCCINIC ANHYDRIDES Clariant Produkte (Deutschland) GmbH (DE) 2007-09-05 EP claimed
WO-2006066720-A1 METHOD FOR PRODUCING ALKENYL SUCCINIC ANHYDRIDES CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2006-06-29 WO claimed
EP-2216372-B1 Compounds for preventing Ghost odour THOR GMBH (DE) 2014-06-04 EP disclosed
US-8350058-B2 Reaction of maleic acid, maleic anhydride, fumaric acid and an alkene which contains 4-250 carbon atoms at from 150 to 250 degrees C. in the presence of a synergistic mixture of a primary antioxidant, a secondary antioxidant, and a metal deactivator CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2013-01-08 US disclosed
US-8287631-B2 Compounds for preventing ghost odour THOR GMBH (DE) 2012-10-16 US disclosed
WO-2012020070-A2 ENHANCEMENT OF THE SKIN DEPIGMENTATION KASRAEE BEHROOZ (CH) 2012-02-16 WO disclosed
EP-2216372-A1 Compounds for preventing Ghost odour THOR GmbH (DE) 2010-08-11 EP disclosed
US-20100186631-A1 Compounds for preventing ghost odour THOR GMBH (DE) 2010-07-29 US disclosed
EP-1828157-B1 METHOD FOR PRODUCING ALKENYL SUCCINIC ANHYDRIDES CLARIANT PRODUKTE DEUTSCHLAND (DE) 2010-03-03 EP disclosed
US-4371651-A PHOTOSTABILITY, HEAT RESISTANCE PHOENIX CHEMICAL CORPORATION (US) 1983-02-01 US disclosed
US-4362831-A A HINDERED AND HETEROCYCLIC AMINE WITH A THIOALKANOIC ACID AMIDE ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1982-12-07 US disclosed
EP-0063180-A1 Beta-diketone and hydrotalcite stabilizer compositions for halogen-containing polymers and polymer compositions containing the same ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1982-10-27 EP disclosed
EP-0046161-A2 Stabilized Polyvinylhalide resin PHOENIX CHEMICAL CORPORATION (US) 1982-02-24 EP disclosed
US-4279805-A Alkylene-bis-thioalkanoic acid amide stabilizers for synthetic resins and synthetic resin compositions containing the same ARGUS CHEMICAL CORPORATION (US) 1981-07-21 US disclosed
US-4269731-A DISCOLORATION INHIBITION; MOLDING MATERIALS ARGUS CHEMICAL CORPORATION (US) 1981-05-26 US disclosed
US-4222931-A Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl ether alcohol or ether, phosphonic acid ester and phenolic antioxidant ARGUS CHEMICAL CORPORATION (US) 1980-09-16 US disclosed
US-4110306-A Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl carboxylic acid ester, a triphosphite, and an acid phosphite or salt thereof ARGUS CHEMICAL CORPORATION (US) 1978-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080108836-A1 Method For Producing Alkenyl Succinic Anhydrides FH, ALDH5A1, SDHB ALOX15 475/4885ALDH1A1 54/4885TP53 2886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.