Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL443253 | 1.00 | PAOX (0.34) | PAOXMC4RALDH1A1MEN1RAD52 | |
| SCHEMBL14477672 | 0.80 | SIGMAR1 (0.43) | ALDH1A1KMT2ASIGMAR1LMNATSHR | |
| SCHEMBL5946047 | 0.80 | ALDH1A1 (0.37) | PAOXALDH1A1MEN1RAD52KMT2A | |
| SCHEMBL10657199 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ALMNATSHR | |
| SCHEMBL28132579 | 0.78 | — | — | |
| SCHEMBL5294936 | 0.78 | — | — | |
| SCHEMBL14210004 | 0.78 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL14258570 | 0.77 | MC4R (0.32) | PAOXMC4RSIGMAR1LMNAKDM4E | |
| SCHEMBL10000696 | 0.77 | DAO (0.35) | ALDH1A1SIGMAR1KDM4ETDP1 | |
| SCHEMBL5858594 | 0.77 | PAOX (0.43) | PAOXALDH1A1MEN1RAD52KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120029177-A1 | HETEROCYCLE-AMINO ACID DERIVATIVES FOR TARGETING CANCER TISSUE AND RADIOACTIVE OR NON-RADIOACTIVE LABELED COMPOUNDS THEREOF | SNU R&DB FOUNDATION (KR) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029177-A1 | HETEROCYCLE-AMINO ACID DERIVATIVES FOR TARGETING CANCER TISSUE AND RADIOACTIVE OR NON-RADIOACTIVE LABELED COMPOUNDS THEREOF | DDC, AAAS, DNPEP | PAOX 1486/4885MC4R 2517/4885ALDH1A1 1843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.