Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL723703 | 0.85 | AKR1B1 (0.40) | AKR1B1KDM4EMAPTGAAALDH1A1 | |
| SCHEMBL20101104 | 0.80 | AKR1B1 (0.40) | AKR1B1KDM4EMAPTGAAALDH1A1 | |
| SCHEMBL10000757 | 0.79 | FASN (0.32) | ERBB2PIM1HKDC1FASN | |
| SCHEMBL11744319 | 0.77 | AKR1B1 (0.42) | AKR1B1KDM4EMAPTGAAALDH1A1 | |
| SCHEMBL12042065 | 0.74 | AKR1B1 (0.41) | AKR1B1KDM4EMAPTGAAALDH1A1 | |
| SCHEMBL12744505 | 0.74 | ERBB2 (0.40) | ERBB2PIM1HKDC1KDM4EALDH1A1 | |
| SCHEMBL11803971 | 0.74 | AKR1B1 (0.44) | AKR1B1KDM4EMAPTGAAALDH1A1 | |
| SCHEMBL10000755 | 0.73 | CA1 (0.31) | KMT2ACA2 | |
| SCHEMBL10000756 | 0.72 | PTGS2 (0.37) | ALDH1A1CYP1A2POLBMEN1KMT2A | |
| SCHEMBL16597206 | 0.71 | ERBB2 (0.39) | ERBB2PIM1HKDC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207229-B1 | Preparation of hydroquinone amide compounds with antioxidant properties | CATALYS SAS (FR) | 2012-06-26 | — | — | US | disclosed |
| US-8207229-B1 | Preparation of hydroquinone amide compounds with antioxidant properties | CATALYS SAS (FR) | 2012-06-26 | — | — | US | disclosed |
| US-8003824-B2 | Preparation of hydroquinone amide compounds with antioxidant properties | CATALYS SAS (FR) | 2011-08-23 | — | — | US | disclosed |
| US-8003824-B2 | Preparation of hydroquinone amide compounds with antioxidant properties | CATALYS SAS (FR) | 2011-08-23 | — | — | US | disclosed |
| EP-2257523-B1 | PREPARATION OF HYDROQUINONE AMIDE COMPOUNDS WITH ANTIOXIDANT PROPERTIES | CATALYS SAS (FR) | 2011-08-10 | — | — | EP | disclosed |
| US-20110021820-A1 | Preparation of Hydroquinone Amide Compounds with Antioxidant Properties | CATALYS SAS (FR) | 2011-01-27 | — | — | US | disclosed |
| US-20110021820-A1 | Preparation of Hydroquinone Amide Compounds with Antioxidant Properties | CATALYS SAS (FR) | 2011-01-27 | — | — | US | disclosed |
| WO-2009115707-A2 | PREPARATION OF HYDROQUINONE AMIDE COMPOUNDS WITH ANTIOXIDANT PROPERTIES. | CATALYS SAS (FR) | 2009-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021820-A1 | Preparation of Hydroquinone Amide Compounds with Antioxidant Properties | NQO1, TYR, AHR | AKR1B1 134/4885ERBB2 2837/4885PIM1 4108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.