Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL723703 | 0.91 | AKR1B1 (0.40) | AKR1B1IMPDH2KDM4EGAAMAPT | |
| SCHEMBL12042065 | 0.85 | AKR1B1 (0.41) | AKR1B1IMPDH2KDM4EGAAMAPT | |
| SCHEMBL11744319 | 0.82 | AKR1B1 (0.42) | AKR1B1KDM4EGAAMAPTALDH1A1 | |
| SCHEMBL10000754 | 0.80 | AKR1B1 (0.36) | AKR1B1IMPDH2KDM4EGAAMAPT | |
| SCHEMBL17772627 | 0.76 | HSP90AB1 (0.42) | IMPDH2KDM4EGAAMAPTALDH1A1 | |
| SCHEMBL12244037 | 0.74 | POLB (0.37) | AKR1B1KDM4EGAAMAPTALDH1A1 | |
| SCHEMBL10606158 | 0.73 | IMPDH2 (0.50) | IMPDH2 | |
| SCHEMBL11803971 | 0.73 | AKR1B1 (0.44) | AKR1B1KDM4EGAAMAPTALDH1A1 | |
| SCHEMBL12257183 | 0.73 | PTGS1 (0.36) | AKR1B1IMPDH2KDM4EGAAMAPT | |
| SCHEMBL12257182 | 0.71 | PTGS1 (0.38) | AKR1B1KDM4EGAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180116219-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180116219-A1 | HERBICIDAL COMPOUNDS | DDT, HPD, HDHD5 | AKR1B1 500/4885IMPDH2 392/4885KDM4E 671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.