Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20101104 | 0.91 | AKR1B1 (0.40) | AKR1B1IMPDH2KDM4EGAAMAPT | |
| SCHEMBL10000754 | 0.85 | AKR1B1 (0.36) | AKR1B1IMPDH2KDM4EGAAMAPT | |
| SCHEMBL11744319 | 0.76 | AKR1B1 (0.42) | AKR1B1KDM4EGAAMAPTALDH1A1 | |
| SCHEMBL9848754 | 0.76 | HDAC11 (0.41) | AKR1B1IMPDH2ALDH1A1MEN1KMT2A | |
| SCHEMBL12042065 | 0.74 | AKR1B1 (0.41) | AKR1B1IMPDH2KDM4EGAAMAPT | |
| SCHEMBL11803971 | 0.73 | AKR1B1 (0.44) | AKR1B1KDM4EGAAMAPTALDH1A1 | |
| SCHEMBL8824097 | 0.73 | KDM4E (0.39) | AKR1B1IMPDH2KDM4EGAAMAPT | |
| SCHEMBL7328569 | 0.73 | TSHR (0.46) | MAPTALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL10386355 | 0.71 | CYP2C19 (0.43) | MAPTCYP1A2CYP3A4CYP2C19CASP7 | |
| SCHEMBL30940421 | 0.71 | AKR1B1 (0.42) | AKR1B1KDM4EGAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583753-A1 | PROCESS FOR THE MANUFACTURE OF ALPHA-TOCOPHERYL ACETATE | DSM IP Assets B.V. (NL) | 2005-10-12 | — | — | EP | claimed |
| EP-1562929-A1 | MANUFACTURE OF TOCOPHERYL ACETATE | DSM IP Assets B.V. (NL) | 2005-08-17 | — | — | EP | claimed |
| WO-2004063182-A1 | PROCESS FOR THE MANUFACTURE OF α-TOCOPHERYL ACETATE | DSM IP ASSETS B.V. (NL) | 2004-07-29 | — | — | WO | claimed |
| WO-2004046126-A1 | MANUFACTURE OF TOCOPHERYL ACETATE | DSM IP ASSETS B.V. (NL) | 2004-06-03 | — | — | WO | claimed |
| EP-2609063-B1 | PROCESS FOR THE MANUFACTURE OF 3,7-DIMETHYL-1-OCTEN-3-OL | DSM IP ASSETS BV (NL) | 2018-05-16 | — | — | EP | disclosed |
| CN-100503593-C | Manufacture of tocopheryl acetate | DSM IP ASSETS BV (NL) | 2009-06-24 | — | — | CN | disclosed |
| EP-1562929-B1 | MANUFACTURE OF TOCOPHERYL ACETATE | DSM IP ASSETS BV (NL) | 2007-11-14 | — | — | EP | disclosed |
| US-20070112206-A1 | Manufacture of tocopheryl acetate | BONRATH WERNER | 2007-05-17 | — | — | US | disclosed |
| EP-1778661-A1 | PROCESS FOR THE MANUFACTURE OF CHROMAN DERIVATIVES, ESPECIALLY ALPHA-TOCOPHEROL AND ALKANOATES THEREOF | DSMIP Assets B.V. (NL) | 2007-05-02 | — | — | EP | disclosed |
| EP-1663937-A2 | SYNTHESIS OF ALPHA-TOCOPHERYL ALKANOATES AND PRECURSORS THEREOF | DSM IP Assets B.V. (NL) | 2006-06-07 | — | — | EP | disclosed |
| EP-1641772-A1 | MANUFACTURE OF TOCOPHEROLS USING A BISMUTH CATALYST | DSM IP Assets B.V. (NL) | 2006-04-05 | — | — | EP | disclosed |
| WO-2005121115-A1 | PROCESS FOR THE MANUFACTURE OF CHROMAN DERIVATIVES, ESPECIALLY α-TOCOPHEROL AND ALKANOATES THEREOF | DSM IP ASSETS B.V. (NL) | 2005-12-22 | — | — | WO | disclosed |
| EP-1583753-A1 | PROCESS FOR THE MANUFACTURE OF ALPHA-TOCOPHERYL ACETATE | DSM IP Assets B.V. (NL) | 2005-10-12 | — | — | EP | disclosed |
| EP-1562929-A1 | MANUFACTURE OF TOCOPHERYL ACETATE | DSM IP Assets B.V. (NL) | 2005-08-17 | — | — | EP | disclosed |
| EP-1562929-A1 | MANUFACTURE OF TOCOPHERYL ACETATE | DSM IP Assets B.V. (NL) | 2005-08-17 | — | — | EP | disclosed |
| WO-2005026142-A2 | SYNTHESIS OF ALPHA-TOCOPHERYL ALKANOATES AND PRECURSORS THEREOF | DSM IP ASSETS B.V. (NL) | 2005-03-24 | — | — | WO | disclosed |
| WO-2005005407-A1 | MANUFACTURE OF TOCOPHEROLS USING A BISMUTH CATALYST | DSM IP ASSETS B.V. (NL) | 2005-01-20 | — | — | WO | disclosed |
| WO-2004063182-A1 | PROCESS FOR THE MANUFACTURE OF α-TOCOPHERYL ACETATE | DSM IP ASSETS B.V. (NL) | 2004-07-29 | — | — | WO | disclosed |
| WO-2004046126-A1 | MANUFACTURE OF TOCOPHERYL ACETATE | DSM IP ASSETS B.V. (NL) | 2004-06-03 | — | — | WO | disclosed |
| WO-2004046126-A1 | MANUFACTURE OF TOCOPHERYL ACETATE | DSM IP ASSETS B.V. (NL) | 2004-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112206-A1 | Manufacture of tocopheryl acetate | TTPA, VKORC1L1, NR1H2 | AKR1B1 144/4885IMPDH2 577/4885KDM4E 938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.