Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | FLT3 | P36888 | 1/20 | 0.63 |
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
| ▸ | AR | P10275 | 1/20 | 0.62 |
| ▸ | APP | P05067 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22230106 | 0.87 | MAPT (0.75) | ABCG2MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL22230108 | 0.87 | MAPT (0.75) | ABCG2MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL19086304 | 0.85 | ABCG2 (0.78) | ABCG2MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL19086305 | 0.85 | ABCG2 (0.78) | ABCG2MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL28549138 | 0.82 | ABCG2 (0.71) | ABCG2MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL997228 | 0.80 | ABCG2 (0.69) | ABCG2MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL997226 | 0.80 | ABCG2 (0.69) | ABCG2MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11959782 | 0.80 | ABCG2 (0.72) | ABCG2MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL25217986 | 0.79 | ABCG2 (1.00) | ABCG2MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL633470 | 0.79 | ABCG2 (1.00) | ABCG2MAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009826-A2 | NOVEL CHALCONE DERIVATIVES WITH CYTOTOXIC ACTIVITY | ADAMED Sp.z o.o. (PL) | 2011-01-27 | — | — | WO | claimed |
| WO-2011009826-A2 | NOVEL CHALCONE DERIVATIVES WITH CYTOTOXIC ACTIVITY | ADAMED Sp.z o.o. (PL) | 2011-01-27 | — | — | WO | disclosed |