Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | STAT1 | P42224 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | MAOA | P21397 | 2/20 | 0.64 |
| ▸ | MAOB | P27338 | 1/20 | 0.64 |
| ▸ | PDE4A | P27815 | 1/20 | 0.64 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.64 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11959782 | 0.95 | ABCG2 (0.72) | ABCG2MEN1KMT2APOLBMAPT | |
| SCHEMBL18099393 | 0.88 | MEN1 (0.74) | ABCG2MEN1KMT2APOLBMAPT | |
| SCHEMBL9717780 | 0.88 | MEN1 (0.74) | ABCG2MEN1KMT2APOLBMAPT | |
| SCHEMBL108665 | 0.86 | MAPT (0.79) | MAPTRAB9AALDH1A1NPSR1NPC1 | |
| SCHEMBL28553855 | 0.86 | MAPT (0.79) | MAPTRAB9AALDH1A1NPSR1NPC1 | |
| SCHEMBL28549137 | 0.85 | RAB9A (0.73) | ABCG2MEN1KMT2APOLBMAPT | |
| SCHEMBL2458579 | 0.84 | ABCG2 (1.00) | ABCG2MEN1KMT2AMAPTLMNA | |
| SCHEMBL2458577 | 0.84 | ABCG2 (1.00) | ABCG2MEN1KMT2AMAPTLMNA | |
| SCHEMBL3192412 | 0.83 | ABCG2 (0.69) | ABCG2MEN1KMT2APOLBMAPT | |
| SCHEMBL3173746 | 0.83 | TNFRSF1A (0.72) | ABCG2MAPTALDH1A1KDM4ETNFRSF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112770755-A | Compositions, syntheses, preparations and uses of analogs derived from position 7 and 9 of platform drug FL118 for treating human diseases | 坎格特生物技术制药有限责任公司 | 2021-05-07 | — | — | CN | disclosed |