Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | AGXT | P21549 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11243675 | 1.00 | MAPT (0.63) | MAPTLOXL2SMN1; SMN2L3MBTL1AGXT | |
| SCHEMBL8688187 | 1.00 | MAPT (0.63) | MAPTLOXL2SMN1; SMN2L3MBTL1AGXT | |
| SCHEMBL19813189 | 1.00 | MAPT (0.63) | MAPTLOXL2SMN1; SMN2L3MBTL1AGXT | |
| SCHEMBL252581 | 0.98 | MAPT (0.60) | MAPTLOXL2SMN1; SMN2L3MBTL1AGXT | |
| SCHEMBL29594271 | 0.93 | LOXL2 (0.56) | MAPTLOXL2SMN1; SMN2L3MBTL1AGXT | |
| SCHEMBL1287509 | 0.93 | LOXL2 (0.56) | MAPTLOXL2SMN1; SMN2L3MBTL1AGXT | |
| Hydrochloric Acid SCHEMBL28989961 | 0.91 | LOXL2 (0.55) | MAPTLOXL2SMN1; SMN2L3MBTL1AGXT | |
| Hydrochloric Acid SCHEMBL27927458 | 0.90 | LOXL2 (0.53) | MAPTLOXL2SMN1; SMN2L3MBTL1AGXT | |
| SCHEMBL6013090 | 0.85 | LOXL2 (0.60) | MAPTLOXL2SMN1; SMN2L3MBTL1AGXT | |
| SCHEMBL2088773 | 0.83 | LOXL2 (0.53) | MAPTLOXL2SMN1; SMN2L3MBTL1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046818-A1 | METHOD FOR PRODUCING CHALCOGEN-CONTAINING CONDENSED POLYCYCLIC COMPOUND | 住友化学株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |