Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | AGXT | P21549 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 6/20 | 0.46 |
| ▸ | DRD1 | P21728 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 5/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8688187 | 0.98 | MAPT (0.63) | MAPTLOXL2AGXTSMN1; SMN2L3MBTL1 | |
| SCHEMBL11243675 | 0.98 | MAPT (0.63) | MAPTLOXL2AGXTSMN1; SMN2L3MBTL1 | |
| SCHEMBL19813189 | 0.98 | MAPT (0.63) | MAPTLOXL2AGXTSMN1; SMN2L3MBTL1 | |
| SCHEMBL10000911 | 0.98 | MAPT (0.63) | MAPTLOXL2AGXTSMN1; SMN2L3MBTL1 | |
| SCHEMBL1287509 | 0.95 | LOXL2 (0.56) | MAPTLOXL2AGXTSMN1; SMN2L3MBTL1 | |
| SCHEMBL29594271 | 0.95 | LOXL2 (0.56) | MAPTLOXL2AGXTSMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL28989961 | 0.93 | LOXL2 (0.55) | MAPTLOXL2AGXTSMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL27927458 | 0.91 | LOXL2 (0.53) | MAPTLOXL2AGXTSMN1; SMN2L3MBTL1 | |
| SCHEMBL6013090 | 0.87 | LOXL2 (0.60) | MAPTLOXL2AGXTSMN1; SMN2L3MBTL1 | |
| SCHEMBL2090531 | 0.82 | LOXL2 (0.55) | MAPTLOXL2AGXTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 463 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054685-A2 | BOTANICAL COMPOSITIONS AND METHODS OF PRODUCTION AND USE THEREOF | ARKANSAS STATE UNIVERSTIY-JONESBORO (US) | 2024-03-14 | — | — | WO | claimed |
| CN-114507866-B | Electrochemical-mediated synthesis method of 2-arylbenzofuran compound | 南京先进生物材料与过程装备研究院有限公司 | 2023-10-31 | — | — | CN | claimed |
| CN-115636807-B | Preparation method and application of two 2-arylbenzofuran derivatives | 南京林业大学 | 2023-09-29 | — | — | CN | claimed |
| CN-115677588-A | 2,3,5,5-tetrasubstituted-4-carbonyl imidazole cyclic nitrone compound, preparation method and application | 中国科学院成都有机化学有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-115636807-A | Preparation method and application of two 2-aryl benzofuran derivatives | 南京林业大学 | 2023-01-24 | — | — | CN | claimed |
| CN-115403523-A | Biquinoline-aryl phenol framework compound with axial chirality and preparation method and application thereof | 中国科学院成都有机化学有限公司 | 2022-11-29 | — | — | CN | claimed |
| CN-114796194-A | Application of DA adduct derived from Morus plant in preparation of beta-G inhibitor | 澳门大学 | 2022-07-29 | — | — | CN | claimed |
| CN-114507866-A | Electrochemical-mediated synthesis method of 2-arylbenzofuran compounds | 南京先进生物材料与过程装备研究院有限公司 | 2022-05-17 | — | — | CN | claimed |
| CN-108997282-B | Arylbenzofuran derivatives having alpha-glucosidase inhibitory activity | 安徽工程大学 | 2022-04-29 | — | — | CN | claimed |
| US-11021454-B2 | Type of aryl benzofuran amidated derivative and medical use thereof | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2021-06-01 | — | — | US | claimed |
| US-5939053-A | TITANIUM, ZINC, CERIUM, ZIRCONIUM AND IRON OXIDES | L'OREAL (FR) | 1999-08-17 | — | — | US | claimed |
| WO-1998023690-A9 | METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS | — | 1998-09-17 | — | — | WO | claimed |
| US-5776440-A | METAL OXIDES AND POLYMERS | L'OREAL (FR) | 1998-07-07 | — | — | US | claimed |
| WO-1998023690-A1 | METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 1998-06-04 | — | — | WO | claimed |
| EP-0601080-B1 | FILTERING COSMETIC COMPOSITION CONTAINING A LIPOSOLUBLE FILTER POLYMER WITH HYDROCARBONATED STRUCTURE AND A FILTER SILICONE | OREAL (FR) | 1995-07-26 | — | — | EP | claimed |
| EP-0555460-B1 | FILTERING COSMETIC COMPOSITION COMPRISING A NANOPIGMENT OF METAL OXIDE AND A LIPOSOLUBLE FILTER POLYMER | OREAL (FR) | 1995-05-31 | — | — | EP | claimed |
| US-5102660-A | For use in cosmetics | L'OREAL (FR) | 1992-04-07 | — | — | US | claimed |
| US-4992204-A | LUMINOPHORE LINKED TO POLYALKYLENE MOIETY | MILIKEN RESEARCH CORPORATION (US) | 1991-02-12 | — | — | US | claimed |
| US-4866159-A | SUNSCREEN AGENTS | L'OREAL (FR) | 1989-09-12 | — | — | US | claimed |
| US-4504644-A | SUNSCREEN AGENTS | L'OREAL (FR) | 1985-03-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11021454-B2 | Type of aryl benzofuran amidated derivative and medical use thereof | XDH, NLRP3, NLRP1 | MAPT 2572/4885LOXL2 327/4885AGXT 109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.