Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 9/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10001066 | 1.00 | GSK3B (0.61) | GSK3BHPGDMAPTALDH1A1PTPN1 | |
| SCHEMBL774179 | 1.00 | GSK3B (0.61) | GSK3BHPGDMAPTALDH1A1PTPN1 | |
| SCHEMBL25424836 | 0.83 | ALDH1A1 (0.64) | HPGDMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL19130858 | 0.82 | GSK3B (0.55) | GSK3BMAPTALDH1A1PTPN1RAB9A | |
| SCHEMBL16754090 | 0.82 | GSK3B (0.55) | GSK3BHPGDMAPTALDH1A1PTPN1 | |
| SCHEMBL702196 | 0.82 | PTPN1 (0.62) | GSK3BHPGDMAPTALDH1A1PTPN1 | |
| SCHEMBL29403777 | 0.82 | PTPN1 (0.62) | GSK3BHPGDMAPTALDH1A1PTPN1 | |
| SCHEMBL205280 | 0.82 | GSK3B (0.80) | GSK3BPTPN1RAB9ANPC1HDAC1 | |
| SCHEMBL303244 | 0.81 | ALDH1A1 (0.61) | HPGDMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL22367578 | 0.81 | ALDH1A1 (0.61) | HPGDMAPTALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165227-A1 | COMPOUNDS AND METHODS FOR DETECTION AND QUANTIFICATION OF CARBOXYLIC ACIDS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165227-A1 | COMPOUNDS AND METHODS FOR DETECTION AND QUANTIFICATION OF CARBOXYLIC ACIDS | AKR1C3, AR, AKR1C4 | GSK3B 4527/4885HPGD 1100/4885MAPT 4517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.