Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.62 |
| ▸ | GSK3B | P49841 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29403777 | 1.00 | PTPN1 (0.62) | PTPN1GSK3BHPGDALDH1A1MAPT | |
| SCHEMBL158933 | 0.85 | SMN1; SMN2 (0.47) | PTPN1HPGDALDH1A1MAPTKDM2B | |
| SCHEMBL29382443 | 0.85 | SMN1; SMN2 (0.47) | PTPN1HPGDALDH1A1MAPTKDM2B | |
| SCHEMBL4224827 | 0.84 | PTPN1 (0.58) | PTPN1GSK3BHPGDALDH1A1MAPT | |
| SCHEMBL11482012 | 0.84 | PTPN1 (0.84) | PTPN1GSK3BHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL24277990 | 0.83 | HPGD (0.44) | PTPN1HPGDALDH1A1MAPTKDM2B | |
| SCHEMBL26735842 | 0.83 | HPGD (0.44) | PTPN1GSK3BHPGDALDH1A1MAPT | |
| Propane SCHEMBL626692 | 0.83 | SMN1; SMN2 (0.46) | PTPN1HPGDALDH1A1MAPTKDM2B | |
| SCHEMBL10001068 | 0.82 | GSK3B (0.61) | PTPN1GSK3BHPGDALDH1A1MAPT | |
| SCHEMBL774179 | 0.82 | GSK3B (0.61) | PTPN1GSK3BHPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240168032-A1 | GLUCOSE BIOSENSORS AND USES THEREOF | UNIV DUKE (US) | 2024-05-23 | — | — | US | claimed |
| EP-3377897-B1 | LACTATE BIOSENSORS AND USES THEREOF | UNIV DUKE (US) | 2024-05-01 | — | — | EP | claimed |
| US-11852637-B2 | Bicarbonate biosensors, calcium biosensors, and uses thereof | DUKE UNIVERSITY (US) | 2023-12-26 | — | — | US | claimed |
| US-20230348884-A1 | Fluorescent Biosensor for Rapid Determination of L-arginine | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2023-11-02 | — | — | US | claimed |
| US-20220244266-A1 | GLUCOSE BIOSENSORS AND USES THEREOF | UNIV DUKE (US) | 2022-08-04 | — | — | US | claimed |
| US-11344223-B2 | Method and an apparatus for measuring acetone concentrations in breath | Solvax Systems Inc. | 2022-05-31 | — | — | US | claimed |
| WO-2022063178-A1 | FLUORESCENT BIOSENSOR FOR RAPID DETERMINATION OF L-ARGININE | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2022-03-31 | — | — | WO | claimed |
| US-20220079469-A1 | METHOD AND AN APPARATUS FOR MEASURING ACETONE CONCENTRATIONS IN BREATH | SOLVAX SYSTEMS INC. / 9717579 CANADA CORP. (CA) | 2022-03-17 | — | — | US | claimed |
| US-11156615-B2 | Glucose biosensors and uses thereof | DUKE UNIVERSITY (US) | 2021-10-26 | — | — | US | claimed |
| US-10961342-B2 | Resin formulation and uses thereof | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2021-03-30 | — | — | US | claimed |
| WO-2010146365-A1 | BIOMETRIC MEMBRANES AND USES THEREOF | AQUAPORIN A/S (DK) | 2010-12-23 | — | — | WO | claimed |
| WO-2009124135-A2 | ANNEXIN-BASED APOPTOSIS MARKERS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2009-10-08 | — | — | WO | claimed |
| US-20090246802-A1 | ANNEXIN-BASED APOPTOSIS MARKERS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2009-10-01 | — | — | US | claimed |
| US-6693091-B2 | CONTAINING PHOTOACTIVE, FLUORESCENT, OR RADIOACTIVE MOIETY | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2004-02-17 | — | — | US | claimed |
| US-20030225052-A1 | Analogs of terpene trilactones from Ginkgo biloba and related compounds and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2003-12-04 | — | — | US | claimed |
| US-20030194370-A1 | Analogs of terpene trilactones from ginkgo biloba for bioorganic and imaging studies | THE TRUSTEES OF COLUMBIA UNIVERSITY | 2003-10-16 | — | — | US | claimed |
| WO-2003082185-A2 | ANALOGS OF TERPENE TRILACTONES FROM GINKGO BILOBA AND RELATED COMPOUNDS AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2003-10-09 | — | — | WO | claimed |
| EP-1335984-A1 | DETERMINATION OF HYDROPHOBIC COENZYME A ESTERS AND OTHER LIPIDS USING A BIOSENSOR COMPRISING A MODIFIED COENZYME A- AND ACYL-COA BINDING PROTEIN (ACBP) | Biosensor APS (DK) | 2003-08-20 | — | — | EP | claimed |
| US-20020142347-A1 | Biosensor | BIOSENSOR APS (DK) | 2002-10-03 | — | — | US | claimed |
| WO-2002061096-A1 | DETERMINATION OF HYDROPHOBIC COENZYME A ESTERS AND OTHER LIPIDS USING A BIOSENS OR COMPRISING A MODIFIED COENZYME A- AND ACYL- BINDING PROTEIN (ACBP) | BIOSENSOR APS (DK) | 2002-08-08 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225052-A1 | Analogs of terpene trilactones from Ginkgo biloba and related compounds and uses thereof | GPBAR1, GRK5, CNR1 | PTPN1 4654/4885GSK3B 1529/4885HPGD 1782/4885 |
| US-20240168032-A1 | GLUCOSE BIOSENSORS AND USES THEREOF | GCK, GCKR, SLC2A4 | PTPN1 777/4885GSK3B 651/4885HPGD 1074/4885 |
| US-20220244266-A1 | GLUCOSE BIOSENSORS AND USES THEREOF | GCK, GCKR, SLC2A4 | PTPN1 777/4885GSK3B 651/4885HPGD 1074/4885 |
| US-20030194370-A1 | Analogs of terpene trilactones from ginkgo biloba for bioorganic and imaging studies | GRK4, GRK1, GNB1 | PTPN1 4777/4885GSK3B 369/4885HPGD 872/4885 |
| US-11156615-B2 | Glucose biosensors and uses thereof | GCK, GCKR, SLC2A4 | PTPN1 777/4885GSK3B 651/4885HPGD 1074/4885 |
| US-11852637-B2 | Bicarbonate biosensors, calcium biosensors, and uses thereof | CA2, CASR, CACYBP | PTPN1 3838/4885GSK3B 2911/4885HPGD 2032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.