Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.66 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.66 |
| ▸ | PDE4A | P27815 | 1/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iopanoic Acid SCHEMBL38976 | 0.79 | LMNA (1.00) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| Iopanoic Acid SCHEMBL29358912 | 0.79 | LMNA (1.00) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL8336112 | 0.77 | LMNA (0.78) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL18922031 | 0.77 | LMNA (0.78) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| Iopanoic Acid SCHEMBL31609799 | 0.74 | LMNA (0.74) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL9002219 | 0.74 | LMNA (0.66) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL9002211 | 0.74 | LMNA (0.66) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL29181466 | 0.74 | LMNA (0.50) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL6247495 | 0.73 | LMNA (0.55) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL9696076 | 0.70 | LMNA (0.53) | LMNACYP2C9CHRM1TBXA2RPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093427-B2 | Construction and screening of solution-phase derived library of fenbufen and ethacrynic acid | NATIONAL TSING HUA UNIVERSITY (TW) | 2012-01-10 | — | — | US | disclosed |