SCHEMBL9696076

SCHEMBL9696076

Nc1c(I)cc(I)c(CCC(=O)O)c1I

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.53
CYP2C9 P11712 2/20 0.53
HIF1A Q16665 2/20 0.53
CHRM1 P11229 1/20 0.53
TBXA2R P21731 1/20 0.53
PDE4A P27815 1/20 0.53
ADRA1A P35348 1/20 0.53
CYP1A2 P05177 1/20 0.53
GPR17 Q13304 5/20 0.40
NPSR1 Q6W5P4 1/20 0.36
PCNA P12004 2/20 0.35
KEAP1 Q14145 1/20 0.34
FFAR1 O14842 2/20 0.34
FFAR4 Q5NUL3 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
POLB P06746 1/20 0.33
THRA P10827 1/20 0.33
THRB P10828 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8095483 0.90 CYP1A2 (0.50) LMNACYP2C9HIF1ACHRM1TBXA2R
SCHEMBL8087407 0.88 LMNA (0.49) LMNACYP2C9HIF1ACHRM1TBXA2R
SCHEMBL8095732 0.87 LMNA (0.48) LMNACYP2C9HIF1ACHRM1TBXA2R
SCHEMBL9695548 0.87 LMNA (0.48) LMNACYP2C9HIF1ACHRM1TBXA2R
SCHEMBL4522860 0.87 LMNA (0.48) LMNACYP2C9HIF1ACHRM1TBXA2R
SCHEMBL9694437 0.87 LMNA (0.48) LMNACYP2C9HIF1ACHRM1TBXA2R
SCHEMBL6247495 0.81 LMNA (0.55) LMNACYP2C9HIF1ACHRM1TBXA2R
SCHEMBL10495782 0.79 GPR17 (0.38) LMNACYP2C9HIF1ACHRM1TBXA2R
SCHEMBL7592876 0.79 HSD17B10 (0.38) LMNACYP2C9HIF1ACHRM1TBXA2R
SCHEMBL3831647 0.76 LMNA (0.44) LMNACYP2C9HIF1ACHRM1TBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11597792-B2 Radiopaque thermoplastic polymer THE TEXAS A&M UNIVERSITY SYSTEM (US) 2023-03-07 US claimed
EP-3704177-A1 RADIOPAQUE THERMOPLASTIC POLYMER The Texas A&M University System (US) 2020-09-09 EP claimed
US-20200247939-A1 RADIOPAQUE THERMOPLASTIC POLYMER THE TEXAS A&M UNIVERSITY SYSTEM 2020-08-06 US claimed
US-12559585-B2 Radiopaque thermoplastic polymer THE TEXAS A&M UNIVERSITY SYSTEM (US) 2026-02-24 US disclosed
US-20230312804-A1 RADIOPAQUE THERMOPLASTIC POLYMER THE TEXAS A&M UNIVERSITY SYSTEM 2023-10-05 US disclosed
US-11597792-B2 Radiopaque thermoplastic polymer THE TEXAS A&M UNIVERSITY SYSTEM (US) 2023-03-07 US disclosed
EP-3704177-A1 RADIOPAQUE THERMOPLASTIC POLYMER The Texas A&M University System (US) 2020-09-09 EP disclosed
US-20200247939-A1 RADIOPAQUE THERMOPLASTIC POLYMER THE TEXAS A&M UNIVERSITY SYSTEM 2020-08-06 US disclosed
US-5093042-A Site-specific for liver; diagnosis of metastatic cancer THE UNIVERSITY OF MICHIGAN (US) 1992-03-03 US disclosed
US-4957729-A CONTRAST THE UNIVERSITY OF MICHIGAN (US) 1990-09-18 US disclosed
US-4873075-A SITE-SPECIFIC TO LIVER AND HEPATOCYTE; SCINTIGRAPHY IMAGING THE UNIVERSITY OF MICHIGAN (US) 1989-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559585-B2 Radiopaque thermoplastic polymer DCX, TPO, TAAR5 LMNA 2686/4885CYP2C9 1539/4885HIF1A 3899/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.