Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23701479 | 0.80 | KDM4E (0.51) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7105773 | 0.79 | ADRB1 (0.70) | KDM4EALDH1A1MEN1KMT2AADRB1 | |
| SCHEMBL3414344 | 0.79 | ADRB1 (0.70) | KDM4EALDH1A1MEN1KMT2AADRB1 | |
| SCHEMBL10063748 | 0.79 | ADRB1 (0.70) | KDM4EALDH1A1MEN1KMT2AADRB1 | |
| SCHEMBL1235260 | 0.79 | KDM4E (0.59) | KDM4EALDH1A1MEN1KMT2AAKR1C3 | |
| SCHEMBL5886084 | 0.79 | KDM4E (0.65) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL4563378 | 0.79 | KDM4E (0.59) | KDM4EALDH1A1KMT2AGAATGFBR1 | |
| SCHEMBL12551114 | 0.79 | KDM4E (0.59) | KDM4EALDH1A1MEN1KMT2AADRB1 | |
| SCHEMBL175496 | 0.79 | KDM4E (0.59) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL12551119 | 0.79 | KDM4E (0.59) | KDM4EALDH1A1LMNAAKR1C3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12018048-B2 | Anthelmintic depsipeptide compounds | Boehringer Ingelheim Animal Health USA Inc. (US) | 2024-06-25 | — | — | US | disclosed |
| EP-4219465-A2 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme Inc (US) | 2023-08-02 | — | — | EP | disclosed |
| WO-2023069884-A1 | KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE | IMAGO BIOSCIENCES, INC. (US) | 2023-04-27 | — | — | WO | disclosed |
| EP-3498701-B1 | PRMT5 INHIBITORS AND USES THEREOF | EPIZYME INC (US) | 2023-02-22 | — | — | EP | disclosed |
| WO-2022260336-A2 | NUCLEOSIDE DERIVATIVE HAVING MULTI-TARGET KINASE INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING CANCER COMPRISING SAME | 퓨쳐메디신 주식회사 | 2022-12-15 | — | — | WO | disclosed |
| US-20220098241-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2022-03-31 | — | — | US | disclosed |
| US-11230571-B2 | Anthelmintic depsipeptide compounds | Boehringer Ingelheim Animal Health USA Inc. (US) | 2022-01-25 | — | — | US | disclosed |
| EP-3922639-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2021-12-15 | — | — | EP | disclosed |
| EP-3517536-B1 | AMINOTRIAZINE DERIVATIVES USEFUL AS TANK-BINDING KINASE INHIBITOR COMPOUNDS | GILEAD SCIENCES INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-3298027-B1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-04-28 | — | — | EP | disclosed |
| US-20080081268-A1 | COLORED CURABLE COMPOSITION, COLOR FILTER AND PRODUCTION METHOD THEREOF | FUJIFILM CORPORATION (JP) | 2008-04-03 | — | — | US | disclosed |
| US-20080081268-A1 | COLORED CURABLE COMPOSITION, COLOR FILTER AND PRODUCTION METHOD THEREOF | FUJIFILM CORPORATION (JP) | 2008-04-03 | — | — | US | disclosed |
| EP-1882684-A1 | PYRROLIDINE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2008-01-30 | — | — | EP | disclosed |
| US-20070202448-A1 | Silver Halide Color Photographic Light-Sensitive Material | FUJI PHOTO FILM CO., LTD. (JP) | 2007-08-30 | — | — | US | disclosed |
| US-7255912-B2 | Antistatic conductive grid pattern with integral logo | EASTMAN KODAK COMPANY (US) | 2007-08-14 | — | — | US | disclosed |
| US-20070184375-A1 | ELECTROSTATIC CHARGE IMAGE DEVELOPING TONER AND IMAGE FORMING METHOD | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2007-08-09 | — | — | US | disclosed |
| US-7223530-B2 | Photographic imaging element with reduced fringing | EASTMAN KODAK COMPANY (US) | 2007-05-29 | — | — | US | disclosed |
| US-7172854-B2 | Photographic color developer solution and processing method by use thereof | KONICA MINOLTA PHOTO IMAGING, INC. (JP) | 2007-02-06 | — | — | US | disclosed |
| US-7163784-B2 | Silver halide emulsion, and silver halide color photographic material using the same | KONICA MINOLTA PHOTO IMAGING, INC. (JP) | 2007-01-16 | — | — | US | disclosed |
| US-7157216-B2 | Silver halide emulsion and silver halide photographic material | KONICA MINOLTA PHOTO IMAGING, INC. (JP) | 2007-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12018048-B2 | Anthelmintic depsipeptide compounds | VIP, DNPEP, DPEP1 | KDM4E 2228/4885ALDH1A1 2924/4885MEN1 1915/4885 |
| US-20220098241-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | VIP, PREP, DNPEP | KDM4E 1071/4885ALDH1A1 2890/4885MEN1 1735/4885 |
| US-11230571-B2 | Anthelmintic depsipeptide compounds | VIP, PREP, DNPEP | KDM4E 1071/4885ALDH1A1 2890/4885MEN1 1735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.