Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19482453 | 0.80 | PSMB5 (0.44) | PSMB5TDP1CASP3SENP8SENP7 | |
| SCHEMBL21988028 | 0.79 | CSF1R (0.44) | PSMB5TDP1CASP3SENP8SENP7 | |
| SCHEMBL5184320 | 0.78 | PDGFRB (0.47) | PSMB5TDP1CASP3SENP8SENP7 | |
| SCHEMBL22167475 | 0.78 | PSMB5 (0.54) | PSMB5TDP1CASP3SENP8SENP7 | |
| SCHEMBL10793933 | 0.78 | ACMSD (0.53) | PSMB5TDP1CASP3SENP8SENP7 | |
| SCHEMBL10991732 | 0.77 | PSMB5 (0.47) | PSMB5TDP1ACMSDPTGS2HDAC1 | |
| SCHEMBL16718964 | 0.75 | PSMB5 (0.46) | PSMB5ACMSDPTGS2HDAC1HDAC2 | |
| SCHEMBL11307172 | 0.75 | PSMB5 (0.46) | PSMB5ACMSDPTGS2HDAC1HDAC2 | |
| SCHEMBL11670468 | 0.75 | PSMB5 (0.46) | PSMB5ACMSDPTGS2HDAC1HDAC2 | |
| SCHEMBL29447639 | 0.75 | PSMB5 (0.41) | PSMB5TDP1CASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150536-B2 | Cycloalkene derivatives and organic electronic devices using the same | LG CHEM, LTD. (KR) | 2015-10-06 | — | — | US | disclosed |
| US-9150536-B2 | Cycloalkene derivatives and organic electronic devices using the same | LG CHEM, LTD. (KR) | 2015-10-06 | — | — | US | disclosed |
| US-20120037892-A1 | NOVEL CYCLOALKENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICES USING THE SAME | LG CHEM, LTD. (KR) | 2012-02-16 | — | — | US | disclosed |
| US-20120037892-A1 | NOVEL CYCLOALKENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICES USING THE SAME | LG CHEM, LTD. (KR) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120037892-A1 | NOVEL CYCLOALKENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICES USING THE SAME | DDT, ICMT, ESD | PSMB5 3114/4885TDP1 3456/4885CASP3 3318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.