Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | IDE | P14735 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HLCS | P50747 | 6/20 | 0.53 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 5/20 | 0.48 |
| ▸ | CA1 | P00915 | 5/20 | 0.48 |
| ▸ | CA2 | P00918 | 5/20 | 0.48 |
| ▸ | CA9 | Q16790 | 5/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13888577 | 1.00 | TDP1 (0.67) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL1727527 | 1.00 | TDP1 (0.67) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL3870139 | 0.94 | TDP1 (0.61) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL18268937 | 0.92 | TDP1 (0.59) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL31224941 | 0.91 | TDP1 (0.72) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL14165464 | 0.91 | TDP1 (0.72) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL9926313 | 0.91 | TDP1 (0.72) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL140972 | 0.91 | TDP1 (0.72) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL13790958 | 0.89 | TDP1 (0.56) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL318637 | 0.88 | TDP1 (0.61) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124364-B2 | Biotin derivatives | GLYCOREX TRANSPLANTATION AB (SE) | 2012-02-28 | — | — | US | disclosed |
| US-8124364-B2 | Biotin derivatives | GLYCOREX TRANSPLANTATION AB (SE) | 2012-02-28 | — | — | US | disclosed |
| US-7473535-B2 | Chemical reagents and methods for detection and quantification of proteins in complex mixtures | THE INSTITUTE FOR SYSTEMS BIOLOGY (US) | 2009-01-06 | — | — | US | disclosed |