Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | IDE | P14735 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HLCS | P50747 | 6/20 | 0.53 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 5/20 | 0.48 |
| ▸ | CA1 | P00915 | 5/20 | 0.48 |
| ▸ | CA2 | P00918 | 5/20 | 0.48 |
| ▸ | CA9 | Q16790 | 5/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13888577 | 1.00 | TDP1 (0.67) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL10002269 | 1.00 | TDP1 (0.67) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL3870139 | 0.94 | TDP1 (0.61) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL18268937 | 0.92 | TDP1 (0.59) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL31224941 | 0.91 | TDP1 (0.72) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL14165464 | 0.91 | TDP1 (0.72) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL9926313 | 0.91 | TDP1 (0.72) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL140972 | 0.91 | TDP1 (0.72) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL13790958 | 0.89 | TDP1 (0.56) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL318637 | 0.88 | TDP1 (0.61) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435800-B2 | Activated labeling reagents and methods for preparing and using the same | BIOSIGHT LTD. (IL) | 2013-05-07 | — | — | US | disclosed |
| WO-2012034613-A3 | REFRIGERATOR | RED BULL GMBH (AT) | 2012-05-10 | — | — | WO | disclosed |
| EP-1329513-B1 | Rapid quantitative analysis of proteins or protein function in complex mixtures | UNIV WASHINGTON (US) | 2011-12-07 | — | — | EP | disclosed |
| US-20090203879-A1 | ACTIVATED LABELING REAGENTS AND METHODS FOR PREPARING AND USING THE SAME | BIOSIGHT LTD | 2009-08-13 | — | — | US | disclosed |
| EP-1814908-A4 | ACTIVATED LABELING REAGENTS AND METHODS FOR PREPARING AND USING THE SAME | BIOSIGHT LTD (IL) | 2009-07-01 | — | — | EP | disclosed |
| EP-1814908-A1 | ACTIVATED LABELING REAGENTS AND METHODS FOR PREPARING AND USING THE SAME | Biosight Ltd. (IL) | 2007-08-08 | — | — | EP | disclosed |
| US-20060234314-A1 | Selective binding and analysis of macromolecules | SHIMADZU RESEARCH LABORATORY (EUROPE) LIMITED (GB) | 2006-10-19 | — | — | US | disclosed |
| WO-2006054310-A1 | ACTIVATED LABELING REAGENTS AND METHODS FOR PREPARING AND USING THE SAME | BIOSIGHT LTD. (IL) | 2006-05-26 | — | — | WO | disclosed |
| US-20050233399-A1 | Rapid quantitative analysis of proteins or protein function in complex mixtures | UNIVERSITY OF WASHINGTON | 2005-10-20 | — | — | US | disclosed |
| EP-1525481-A2 | SELECTIVE BINDING AND ANALYSIS OF MACROMOLECULES: QUANTITATIVE ANALYSIS OF PROTEINS IN COMPLEX MIXTURES | Shimadzu Research Laboratory (Europe) Ltd. (GB) | 2005-04-27 | — | — | EP | disclosed |
| US-6852544-B2 | Rapid quantitative analysis of proteins or protein function in complex mixtures | UNIVERSITY OF WASHINGTON (US) | 2005-02-08 | — | — | US | disclosed |
| US-6670194-B1 | Mass spectrometry; screening for changes in the expression of enzymatic activity of specific proteins induced by absence, deficiency or excess of a given protein | UNIVERSITY OF WASHINGTON | 2003-12-30 | — | — | US | disclosed |
| WO-2003102592-A2 | SELECTIVE BINDING AND ANALYSIS OF MACROMOLECULES: QUANTITATIVE ANALYSIS OF PROTEINS IN COMPLEX MIXTURES | SHIMADZU RESEARCH LABORATORY (EUROPE) LIMITED (GB) | 2003-12-11 | — | — | WO | disclosed |
| EP-1105517-B1 | RAPID QUANTITATIVE ANALYSIS OF PROTEINS OR PROTEIN FUNCTION IN COMPLEX MIXTURES | UNIV WASHINGTON (US) | 2003-10-29 | — | — | EP | disclosed |
| EP-1329513-A1 | Rapid quantitative analysis of proteins or protein function in complex mixtures | UNIVERSITY OF WASHINGTON (US) | 2003-07-23 | — | — | EP | disclosed |
| US-20030087322-A9 | Rapid quantitative analysis of proteins or protein function in complex mixtures | UNIVERSITY OF WASHINGTON | 2003-05-08 | — | — | US | disclosed |
| US-20020076739-A1 | Rapid quantitative analysis of proteins or protein function in complex mixtures | UNIVERSITY OF WASHINGTON | 2002-06-20 | — | — | US | disclosed |
| EP-1105517-A4 | RAPID QUANTITATIVE ANALYSIS OF PROTEINS OR PROTEIN FUNCTION IN COMPLEX MIXTURES | UNIV WASHINGTON (US) | 2001-09-19 | — | — | EP | disclosed |
| EP-1105517-A1 | RAPID QUANTITATIVE ANALYSIS OF PROTEINS OR PROTEIN FUNCTION IN COMPLEX MIXTURES | UNIVERSITY OF WASHINGTON (US) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000011208-A1 | RAPID QUANTITATIVE ANALYSIS OF PROTEINS OR PROTEIN FUNCTION IN COMPLEX MIXTURES | UNIVERSITY OF WASHINGTON (US) | 2000-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020076739-A1 | Rapid quantitative analysis of proteins or protein function in complex mixtures | PRTN3, RPS27A, PA2G4 | TDP1 4040/4885MEN1 2976/4885ABL1 3933/4885 |
| US-20030087322-A9 | Rapid quantitative analysis of proteins or protein function in complex mixtures | PRTN3, RPS27A, PA2G4 | TDP1 4040/4885MEN1 2976/4885ABL1 3933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.