Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | IDE | P14735 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | HLCS | P50747 | 6/20 | 0.50 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 6/20 | 0.47 |
| ▸ | CA1 | P00915 | 6/20 | 0.47 |
| ▸ | CA2 | P00918 | 6/20 | 0.47 |
| ▸ | CA9 | Q16790 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biotin SCHEMBL4360688 | 0.96 | TDP1 (0.64) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL3870139 | 0.88 | TDP1 (0.61) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL10002269 | 0.88 | TDP1 (0.67) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL13888577 | 0.88 | TDP1 (0.67) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL1727527 | 0.88 | TDP1 (0.67) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL318962 | 0.87 | TDP1 (0.53) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL5903549 | 0.86 | TDP1 (0.48) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL14165464 | 0.85 | TDP1 (0.72) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL140972 | 0.85 | TDP1 (0.72) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL31224941 | 0.85 | TDP1 (0.72) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1684810-B1 | Polybiotin compounds for magnetic resonance imaging and drug delivery | GEN HOSPITAL CORP (US) | 2013-09-25 | — | — | EP | disclosed |
| WO-2012034613-A3 | REFRIGERATOR | RED BULL GMBH (AT) | 2012-05-10 | — | — | WO | disclosed |
| US-8092782-B2 | Polybiotin compounds of magnetic resonance imaging and drug delivery | THE GENERAL HOSPITAL CORPORATION (US) | 2012-01-10 | — | — | US | disclosed |
| EP-1329513-B1 | Rapid quantitative analysis of proteins or protein function in complex mixtures | UNIV WASHINGTON (US) | 2011-12-07 | — | — | EP | disclosed |
| US-7544518-B2 | Rapid quantitative analysis of proteins or protein function in complex mixtures | UNIVERSITY OF WASHINGTON (US) | 2009-06-09 | — | — | US | disclosed |
| EP-1684810-A4 | POLYBIOTIN COMPOUNDS FOR MAGNETIC RESONANCE IMAGINING AND DRUG DELIVERY | GEN HOSPITAL CORP (US) | 2009-05-27 | — | — | EP | disclosed |
| US-20090010845-A1 | Polybiotin Compounds of Magnetic Resonance Imaging and Drug Delivery | THE GENERAL HOSPITAL CORPORATION (US) | 2009-01-08 | — | — | US | disclosed |
| US-7438893-B2 | Polybiotin compounds for magnetic resonance imaging and drug delivery | MASSACHUSETTS GENERAL HOSPITAL (US) | 2008-10-21 | — | — | US | disclosed |
| US-7141676-B1 | Water soluble multi-biotin-containing compounds | UNIVERSITY OF WASHINGTON (US) | 2006-11-28 | — | — | US | disclosed |
| US-20060228325-A1 | Water soluble multi-biotin-containing compounds | WILBUR D S | 2006-10-12 | — | — | US | disclosed |
| EP-1329513-A1 | Rapid quantitative analysis of proteins or protein function in complex mixtures | UNIVERSITY OF WASHINGTON (US) | 2003-07-23 | — | — | EP | disclosed |
| US-20030087322-A9 | Rapid quantitative analysis of proteins or protein function in complex mixtures | UNIVERSITY OF WASHINGTON | 2003-05-08 | — | — | US | disclosed |
| US-20020076739-A1 | Rapid quantitative analysis of proteins or protein function in complex mixtures | UNIVERSITY OF WASHINGTON | 2002-06-20 | — | — | US | disclosed |
| EP-1196199-A4 | WATER SOLUBLE MULTI-BIOTIN-CONTAINING COMPOUNDS | UNIV WASHINGTON (US) | 2002-06-19 | — | — | EP | disclosed |
| EP-1196199-A2 | WATER SOLUBLE MULTI-BIOTIN-CONTAINING COMPOUNDS | University of Washington (US) | 2002-04-17 | — | — | EP | disclosed |
| EP-1105517-A4 | RAPID QUANTITATIVE ANALYSIS OF PROTEINS OR PROTEIN FUNCTION IN COMPLEX MIXTURES | UNIV WASHINGTON (US) | 2001-09-19 | — | — | EP | disclosed |
| EP-1105517-A1 | RAPID QUANTITATIVE ANALYSIS OF PROTEINS OR PROTEIN FUNCTION IN COMPLEX MIXTURES | UNIVERSITY OF WASHINGTON (US) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000072802-A2 | WATER SOLUBLE MULTI-BIOTIN-CONTAINING COMPOUNDS | UNIVERSITY OF WASHINGTON (US) | 2000-12-07 | — | — | WO | disclosed |
| WO-2000011208-A1 | RAPID QUANTITATIVE ANALYSIS OF PROTEINS OR PROTEIN FUNCTION IN COMPLEX MIXTURES | UNIVERSITY OF WASHINGTON (US) | 2000-03-02 | — | — | WO | disclosed |
| WO-1997029114-A1 | BIOTIN-CONTAINING COMPOUNDS, BIOTINYLATION REAGENTS AND METHODS | BOARD OF REGENTS OF THE UNIVERSITY OF WASHINGTON (US) | 1997-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020076739-A1 | Rapid quantitative analysis of proteins or protein function in complex mixtures | PRTN3, RPS27A, PA2G4 | TDP1 4040/4885MEN1 2976/4885ABL1 3933/4885 |
| US-20060228325-A1 | Water soluble multi-biotin-containing compounds | BTD, HLCS, VNN1 | TDP1 2706/4885MEN1 3462/4885ABL1 4752/4885 |
| US-20090010845-A1 | Polybiotin Compounds of Magnetic Resonance Imaging and Drug Delivery | BTD, BCAT1, BRD4 | TDP1 3576/4885MEN1 336/4885ABL1 1751/4885 |
| US-20030087322-A9 | Rapid quantitative analysis of proteins or protein function in complex mixtures | PRTN3, RPS27A, PA2G4 | TDP1 4040/4885MEN1 2976/4885ABL1 3933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.