SCHEMBL10003355

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10003629	0.89	NOD2 (0.41)	NOD2NOD1HSD11B1ALOX5PTGDR2
	SCHEMBL10002780	0.87	NOD2 (0.43)	NOD2NOD1HSD11B1ALOX5SCN9A
	SCHEMBL10004859	0.85	NOD2 (0.46)	TRPV1NOD2NOD1HSD11B1ALOX5
	SCHEMBL10003877	0.83	TRPV1 (0.38)	TRPV1NOD2NOD1HSD11B1ALOX5
	SCHEMBL10003874	0.83	TRPV1 (0.38)	TRPV1NOD2NOD1HSD11B1ALOX5
	SCHEMBL11932281	0.83	TRPV1 (0.38)	TRPV1NOD2NOD1HSD11B1ALOX5
	SCHEMBL10003478	0.83	NOD1 (0.46)	NOD2NOD1HSD11B1ALOX5PTGDR2
	SCHEMBL10003680	0.83	NOD2 (0.38)	NOD2NOD1ALOX5SCN9AALDH1A1
	SCHEMBL10003846	0.82	NOD2 (0.41)	NOD2NOD1ALOX5SCN9AALDH1A1
	SCHEMBL10003270	0.81	NOD2 (0.38)	NOD2NOD1ALOX5SCN9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.