Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192855 | 0.85 | ABCB1 (0.40) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL15942633 | 0.82 | ABCB1 (0.43) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL3808753 | 0.75 | ABCB1 (0.46) | ABCB1USP2CFTRPAX8ATM | |
| Hydrochloric Acid SCHEMBL3808756 | 0.74 | USP2 (0.46) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL20600864 | 0.73 | USP2 (0.53) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL20600870 | 0.73 | USP2 (0.53) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL30388412 | 0.73 | USP2 (0.53) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL20600851 | 0.72 | ABCB1 (0.73) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL20600852 | 0.72 | ABCB1 (0.73) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL18350821 | 0.72 | ABCB1 (0.73) | ABCB1USP2CFTRPAX8ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11857509-B2 | Liposome compositions and methods of use thereof | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) | 2024-01-02 | — | — | US | disclosed |
| US-20230181744-A1 | COMPOUND FOR PREVENTING OR TREATING LIPID METABOLISM-RELATED DISEASES | FUDAN UNIVERSITY (CN) | 2023-06-15 | — | — | US | disclosed |
| US-20180064648-A1 | Liposome Structures And Methods of Use Thereof | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES | 2018-03-08 | — | — | US | disclosed |
| US-9750693-B2 | Liposome structures and methods of use thereof | RHODE ISLAND COUNCIL ON POSTSECONDARY EDUCATION (STATUTORY SUCCESSOR TO RHODE ISLAND BOARD OF GOVERNORS FOR HIGHER EDUCATION) (US) | 2017-09-05 | — | — | US | disclosed |
| US-20150086617-A1 | Liposome Structures And Methods of Use Thereof | YALE UNIVERSITY (US) | 2015-03-26 | — | — | US | disclosed |
| US-8846081-B2 | Liposome compositions and methods of use thereof | RHODE ISLAND BOARD OF GOVERNORS FOR HIGHER EDUCATION (US) | 2014-09-30 | — | — | US | disclosed |
| US-20120039990-A1 | Liposome Compositions and Methods of Use Thereof | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230181744-A1 | COMPOUND FOR PREVENTING OR TREATING LIPID METABOLISM-RELATED DISEASES | MAP1LC3B, MAP1LC3A, SQSTM1 | ABCB1 584/4885USP2 2259/4885CFTR 4404/4885 |
| US-20180064648-A1 | Liposome Structures And Methods of Use Thereof | LIPA, PHLPP2, PHLPP1 | ABCB1 3067/4885USP2 877/4885CFTR 2575/4885 |
| US-11857509-B2 | Liposome compositions and methods of use thereof | LIPA, PHLPP1, PHLPP2 | ABCB1 2883/4885USP2 1114/4885CFTR 2633/4885 |
| US-20120039990-A1 | Liposome Compositions and Methods of Use Thereof | LIPA, PHLPP1, PHLPP2 | ABCB1 2883/4885USP2 1114/4885CFTR 2633/4885 |
| US-20150086617-A1 | Liposome Structures And Methods of Use Thereof | LIPA, PHLPP2, PHLPP1 | ABCB1 3067/4885USP2 877/4885CFTR 2575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.