Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ4 | P56696 | 3/20 | 0.47 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10281196 | 0.94 | KCNQ4 (0.50) | KCNQ4KCNQ5HPGDCYP1A2CYP2C9 | |
| SCHEMBL18493542 | 0.84 | HPGD (0.39) | HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4300793 | 0.82 | KCNQ4 (0.45) | KCNQ4KCNQ5PTPN11GABRA1GABRG2 | |
| SCHEMBL14355613 | 0.82 | PDK1 (0.45) | KCNQ4KCNQ5PTPN11GABRA1GABRG2 | |
| SCHEMBL2134811 | 0.82 | AAK1 (0.44) | KCNQ4KCNQ5PTPN11GABRA1GABRG2 | |
| SCHEMBL30931981 | 0.82 | CYP17A1 (0.49) | KCNQ4KCNQ5PTPN11GABRA1GABRG2 | |
| SCHEMBL10006061 | 0.82 | GABRA5 (0.43) | KCNQ4KCNQ5HPGDCYP1A2CYP2C9 | |
| SCHEMBL21338408 | 0.79 | KCNQ4 (0.40) | KCNQ4KCNQ5BRD9PTPN11GABRA1 | |
| SCHEMBL10006006 | 0.79 | AAK1 (0.46) | KCNQ4KCNQ5HPGDCYP1A2CYP2C9 | |
| SCHEMBL5562552 | 0.78 | KMT2A (0.43) | KCNQ4KCNQ5CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9394279-B2 | Anti-viral compounds | ABBVIE INC. (US) | 2016-07-19 | — | — | US | disclosed |
| US-20120172290-A1 | Anti-Viral Compounds | ABBOTT LABORATORIES (US) | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172290-A1 | Anti-Viral Compounds | HAVCR2, EIF2AK2, MAVS | KCNQ4 4679/4885KCNQ5 4698/4885HPGD 3586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.