Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1000895 | 1.00 | KMT2A (0.50) | KMT2AALDH1A1NPC1RAB9ANFKB1 | |
| SCHEMBL16167075 | 0.79 | KMT2A (0.53) | KMT2AALDH1A1NPC1RAB9ANFKB1 | |
| SCHEMBL223592 | 0.79 | ALDH1A1 (0.60) | KMT2AALDH1A1NPC1RAB9ANFKB1 | |
| SCHEMBL223591 | 0.79 | ALDH1A1 (0.60) | KMT2AALDH1A1NPC1RAB9ANFKB1 | |
| SCHEMBL138933 | 0.76 | ALDH1A1 (0.58) | KMT2AALDH1A1NPC1RAB9ANFKB1 | |
| SCHEMBL16642045 | 0.76 | KMT2A (0.50) | KMT2AALDH1A1NPC1RAB9ANFKB1 | |
| SCHEMBL138932 | 0.76 | ALDH1A1 (0.58) | KMT2AALDH1A1NPC1RAB9ANFKB1 | |
| SCHEMBL100984 | 0.76 | KMT2A (0.50) | KMT2AALDH1A1NPC1RAB9ANFKB1 | |
| SCHEMBL27647042 | 0.76 | KMT2A (0.50) | KMT2AALDH1A1NPC1RAB9ANFKB1 | |
| SCHEMBL14627607 | 0.76 | KMT2A (0.50) | KMT2AALDH1A1NPC1RAB9ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874871-B1 | WATER SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | GE HEALTHCARE UK LTD (GB) | 2012-10-03 | — | — | EP | disclosed |
| US-8148539-B2 | Cyanine dye labelling reagents | GE HEALTHCARE UK LIMITED (GB) | 2012-04-03 | — | — | US | disclosed |
| EP-1678258-B1 | CYANINE DYE LABELLING REAGENTS | GE HEALTHCARE LTD (GB) | 2011-08-31 | — | — | EP | disclosed |
| EP-2360211-A1 | Fluorescently-labelled target components | GE Healthcare Limited (GB) | 2011-08-24 | — | — | EP | disclosed |
| EP-2270106-A2 | Indolium compounds containing fluoro-substituents | GE Healthcare UK Limited (GB) | 2011-01-05 | — | — | EP | disclosed |
| US-20100267937-A1 | Cyanine Dye Labelling Reagents | WEST RICHARD M | 2010-10-21 | — | — | US | disclosed |
| US-20100249385-A1 | WATER-SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | GE HEALTHCARE UK LIMITED (GB) | 2010-09-30 | — | — | US | disclosed |
| US-7767829-B2 | Water-soluble fluoro-substituted cyanine dyes as reactive fluorescence labelling reagents | GE HEALTHCARE UK LIMITED (GB) | 2010-08-03 | — | — | US | disclosed |
| US-7750163-B2 | Cyanine dye labelling reagents | GE Healthcare U.K. Limited (GB) | 2010-07-06 | — | — | US | disclosed |
| US-20100015054-A1 | FLUORO-SUBSTITUTED BENZOXAZOLE POLYMETHINE DYES | GE HEALTHCARE UK LIMITED (GB) | 2010-01-21 | — | — | US | disclosed |
| WO-2008040994-A2 | FLUORO-SUBSTITUTED BENZOXAZOLE POLYMETHINE DYES | GE HEALTHCARE UK LIMITED (GB) | 2008-04-10 | — | — | WO | disclosed |
| WO-2008015415-A2 | ASYMMETRIC FLUORO-SUBSTITUTED POLYMETHINE DYES | GE HEALTHCARE AS (NO) | 2008-02-07 | — | — | WO | disclosed |
| EP-1874871-A1 | WATER SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | GE Healthcare UK Limited (GB) | 2008-01-09 | — | — | EP | disclosed |
| US-20070203343-A1 | Cyanine Dye Labelling Reagents | GE HEALTHCARE UK LIMITED (GB) | 2007-08-30 | — | — | US | disclosed |
| US-7172907-B2 | Cyanine dye labelling reagents with meso-substitution | GE HEALTHCARE BIO-SCIENCES CORP. (US) | 2007-02-06 | — | — | US | disclosed |
| US-20060239922-A1 | WATER-SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | GE HEALTHCARE UK LIMITED (GB) | 2006-10-26 | — | — | US | disclosed |
| WO-2006111726-A1 | WATER SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | GE HEALTHCARE UK LIMITED (GB) | 2006-10-26 | — | — | WO | disclosed |
| EP-1678258-A1 | CYANINE DYE LABELLING REAGENTS | GE Healthcare Limited (GB) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005044923-A1 | CYANINE DYE LABELLING REAGENTS | GE HEALTHCARE LIMITED (GB) | 2005-05-19 | — | — | WO | disclosed |
| US-20040186278-A1 | Cyanine dye labelling reagents with meso-substitution | GLOBAL LIFE SCIENCES SOLUTIONS USA LLC | 2004-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060239922-A1 | WATER-SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | TPD52L2, MRPL21, MRPL9 | KMT2A 3156/4885ALDH1A1 2125/4885NPC1 4332/4885 |
| US-20070203343-A1 | Cyanine Dye Labelling Reagents | IK, H1-5, H1-3 | KMT2A 1319/4885ALDH1A1 4348/4885NPC1 4718/4885 |
| US-20100267937-A1 | Cyanine Dye Labelling Reagents | IK, H1-5, H1-3 | KMT2A 1202/4885ALDH1A1 4309/4885NPC1 4730/4885 |
| US-20100015054-A1 | FLUORO-SUBSTITUTED BENZOXAZOLE POLYMETHINE DYES | QRFPR, MSR1, NPY1R | KMT2A 2414/4885ALDH1A1 3683/4885NPC1 4692/4885 |
| US-20100249385-A1 | WATER-SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | TPD52L2, MRPL9, MRPL21 | KMT2A 3165/4885ALDH1A1 2134/4885NPC1 4310/4885 |
| US-20040186278-A1 | Cyanine dye labelling reagents with meso-substitution | HCCS, CBR3, CYCS | KMT2A 2010/4885ALDH1A1 2632/4885NPC1 3118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.