SCHEMBL138933

SCHEMBL138933

O=CC=CNc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.58
KMT2A Q03164 2/20 0.50
NPC1 O15118 6/20 0.48
RAB9A P51151 5/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
NFKB1 P19838 2/20 0.48
NFKB2 Q00653 2/20 0.48
RELA Q04206 2/20 0.48
NPSR1 Q6W5P4 1/20 0.48
MAPK1 P28482 3/20 0.44
LMNA P02545 2/20 0.44
TRPA1 O75762 1/20 0.44
ALOX5 P09917 1/20 0.44
IDO1 P14902 1/20 0.40
TDP1 Q9NUW8 3/20 0.38
HSD17B10 Q99714 3/20 0.38
CTSD P07339 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.37
MAPT P10636 2/20 0.37
GAA P10253 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL138932 1.00 ALDH1A1 (0.58) ALDH1A1KMT2ANPC1RAB9ASMN1; SMN2
Aniline SCHEMBL14629839 0.90 ALDH1A1 (0.48) ALDH1A1KMT2ANPC1RAB9ASMN1; SMN2
Aniline SCHEMBL27544480 0.81 KMT2A (0.47) ALDH1A1KMT2ANPC1RAB9ASMN1; SMN2
Hydrochloric Acid SCHEMBL28747397 0.81 ALDH1A1 (0.55) ALDH1A1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL223592 0.79 ALDH1A1 (0.60) ALDH1A1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL223591 0.79 ALDH1A1 (0.60) ALDH1A1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL30513185 0.77 MAPT (0.52) ALDH1A1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL10716543 0.77 CTSD (0.42) ALDH1A1KMT2ACTSDL3MBTL1GAA
SCHEMBL10863760 0.77 CTSD (0.42) ALDH1A1KMT2ACTSDL3MBTL1GAA
SCHEMBL27817562 0.77 ALDH1A1 (0.33) ALDH1A1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025095666-A1 NOVEL OXOCYANINE-BASED COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF 포항공과대학교 산학협력단 2025-05-08 WO disclosed
US-20240132948-A1 Cyanine Dyes PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2024-04-25 US disclosed
CN-116178673-A Process for preparing composite material by vacuum infusion method 镇江利德尔复合材料有限公司 2023-05-30 CN disclosed
US-11624089-B2 Cyanine dyes PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2023-04-11 US disclosed
US-20200232023-A1 CYANINE DYES PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2020-07-23 US disclosed
EP-2715416-B1 COLORED RADIATION-SENSITIVE COMPOSITION FOR COLOR FILTER, PATTERN FORMING METHOD, COLOR FILTER AND METHOD OF PRODUCING THE SAME, AND SOLID-STATE IMAGE SENSOR FUJIFILM CORP (JP) 2019-10-30 EP disclosed
US-10392659-B2 Cyanine dyes PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2019-08-27 US disclosed
EP-2264526-B1 PHOTOSENSITIVE TRANSPARENT RESIN COMPOSITION, PROCESS FOR PRODUCTION OF COLOR FILTERS, AND COLOR FILTERS FUJIFILM CORP (JP) 2019-05-22 EP disclosed
US-10159757-B2 Fluorescent conjugates SURGIMAB S.A.S. (FR) 2018-12-25 US disclosed
US-20180216060-A1 METHODS AND MEANS FOR THE MODIFICATION OF CELL SURFACES ACADEMISCH ZIEKENHUIS LEIDEN (ALSO ACTING UNDER TH E NAME OF LEIDEN UNIVERSITY MEDICAL CENTER) (NL) 2018-08-02 US disclosed
EP-0136847-A2 Photographically useful chalcogenazolylidene and chalcogenazolium dyes and methods for their preparation EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-04-10 EP disclosed
EP-0120601-A2 Oxidative imaging MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-10-03 EP disclosed
EP-0015602-B1 NOVEL LIGHT-ABSORBING METHINE DYES AND PHOTOGRAPHIC MATERIALS CONTAINING THEM AGFA-GEVAERT N.V. (BE) 1983-09-21 EP disclosed
US-4266014-A Photographic materials containing light absorbing methine dyes AGFA-GEVAERT N.V. (BE) 1981-05-05 US disclosed
US-4266014-A Photographic materials containing light absorbing methine dyes AGFA-GEVAERT N.V. (BE) 1981-05-05 US disclosed
US-4239901-A ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1980-12-16 US disclosed
EP-0015602-A1 Novel light-absorbing methine dyes and photographic materials containing them AGFA-GEVAERT N.V. (BE) 1980-09-17 EP disclosed
EP-0015602-A1 Novel light-absorbing methine dyes and photographic materials containing them AGFA-GEVAERT N.V. (BE) 1980-09-17 EP disclosed
US-4088497-A Acutance agents for use in thermally-developable photosensitive compositions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-05-09 US disclosed
US-4033948-A METHINE ARYLIDENE DYES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1977-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240132948-A1 Cyanine Dyes ABCG2, IK, ACR ALDH1A1 1447/4885KMT2A 2564/4885NPC1 2122/4885
US-10392659-B2 Cyanine dyes ABCG2, IK, ACR ALDH1A1 1447/4885KMT2A 2564/4885NPC1 2122/4885
US-10159757-B2 Fluorescent conjugates MKI67, CD99, F13A1 ALDH1A1 435/4885KMT2A 1822/4885NPC1 2891/4885
US-11624089-B2 Cyanine dyes ABCG2, IK, ACR ALDH1A1 1447/4885KMT2A 2564/4885NPC1 2122/4885
US-20200232023-A1 CYANINE DYES ABCG2, IK, ACR ALDH1A1 1447/4885KMT2A 2564/4885NPC1 2122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.