SCHEMBL10009902

SCHEMBL10009902

CCCCN(CCCCOC(C)=O)c1ccc(C=O)c(OCc2ccccc2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.46
SLC16A3 O15427 2/20 0.43
SLC16A1 P53985 2/20 0.43
ALDH1A1 P00352 4/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
HDAC8 Q9BY41 1/20 0.38
KDM4E B2RXH2 1/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
CYP3A4 P08684 1/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TRPM8 Q7Z2W7 1/20 0.37
CNR2 P34972 1/20 0.37
PLA2G2D Q9UNK4 1/20 0.37
PTGES O14684 1/20 0.36
ALOX5 P09917 1/20 0.36
PPARG P37231 1/20 0.36
PSEN1 P49768 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29368301 1.00 BACE1 (0.46) BACE1SLC16A3SLC16A1ALDH1A1L3MBTL1
SCHEMBL21191502 0.96 BACE1 (0.46) BACE1SLC16A3SLC16A1ALDH1A1L3MBTL1
SCHEMBL21191517 0.89 BACE1 (0.48) BACE1SLC16A3SLC16A1ALDH1A1L3MBTL1
SCHEMBL11934279 0.89 BACE1 (0.48) BACE1SLC16A3SLC16A1ALDH1A1L3MBTL1
SCHEMBL10009490 0.89 BACE1 (0.49) BACE1SLC16A3SLC16A1ALDH1A1L3MBTL1
SCHEMBL12837046 0.87 SLC16A3 (0.40) BACE1SLC16A3SLC16A1ALDH1A1L3MBTL1
SCHEMBL10009419 0.87 BACE1 (0.47) BACE1SLC16A3SLC16A1ALDH1A1L3MBTL1
SCHEMBL20954298 0.82 BACE1 (0.43) BACE1ALDH1A1HDAC8TSHRERN1
SCHEMBL29368606 0.82 BACE1 (0.43) BACE1ALDH1A1HDAC8TSHRERN1
SCHEMBL10009948 0.81 BACE1 (0.40) BACE1SLC16A3SLC16A1ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3480224-B1 ELECTRO-OPTIC POLYMER NAT INST INF & COMM TECH (JP) 2024-06-12 EP disclosed
CN-109415468-B Electro-optical polymers 国立研究开发法人情报通信研究机构 2024-06-07 CN disclosed
US-20230367084-A1 Determination Method, Optical Control Element and Manufacturing Method Thereof NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY (JP) 2023-11-16 US disclosed
US-11236188-B2 Electro-optic polymer NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY (JP) 2022-02-01 US disclosed
US-11236188-B2 Electro-optic polymer NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY (JP) 2022-02-01 US disclosed
US-10754064-B2 Second-order nonlinear optical compound and nonlinear optical element comprising the same NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY (JP) 2020-08-25 US disclosed
US-10754064-B2 Second-order nonlinear optical compound and nonlinear optical element comprising the same NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY (JP) 2020-08-25 US disclosed
US-20190225728-A1 ELECTRO-OPTIC POLYMER NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY (JP) 2019-07-25 US disclosed
US-20190225728-A1 ELECTRO-OPTIC POLYMER NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY (JP) 2019-07-25 US disclosed
EP-3480224-A1 ELECTRO-OPTIC POLYMER National Institute of Information and Communications Technology (JP) 2019-05-08 EP disclosed
US-9488755-B2 Second-order nonlinear optical compound and nonlinear optical element comprising the same NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY (JP) 2016-11-08 US disclosed
US-20160318889-A1 SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME NAT INST INF & COMM TECH (JP) 2016-11-03 US disclosed
US-20160318889-A1 SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME NAT INST INF & COMM TECH (JP) 2016-11-03 US disclosed
US-20150048284-A1 SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME NAT INST INF & COMM TECH (JP) 2015-02-19 US disclosed
US-20150048284-A1 SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME NAT INST INF & COMM TECH (JP) 2015-02-19 US disclosed
US-8846955-B2 Second-order nonlinear optical compound and nonlinear optical element comprising the same NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY (JP) 2014-09-30 US disclosed
US-8846955-B2 Second-order nonlinear optical compound and nonlinear optical element comprising the same NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY (JP) 2014-09-30 US disclosed
US-20120172599-A1 SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 2012-07-05 US disclosed
US-20120172599-A1 SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 2012-07-05 US disclosed
WO-2011024774-A1 SECOND-ORDER NON-LINEAR OPTICAL COMPOUND AND NON-LINEAR OPTICAL ELEMENT COMPRISING SAME 独立行政法人情報通信研究機構 (JP) 2011-03-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190225728-A1 ELECTRO-OPTIC POLYMER UACA, ELAVL1, EYA3 BACE1 4855/4885SLC16A3 84/4885SLC16A1 187/4885
US-20160318889-A1 SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME OGFOD1, OCIAD2, OCIAD1 BACE1 4124/4885SLC16A3 3538/4885SLC16A1 4423/4885
US-11236188-B2 Electro-optic polymer UACA, ELAVL1, EYA3 BACE1 4855/4885SLC16A3 84/4885SLC16A1 187/4885
US-20150048284-A1 SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME OGFOD1, OCIAD2, OCIAD1 BACE1 4124/4885SLC16A3 3538/4885SLC16A1 4423/4885
US-10754064-B2 Second-order nonlinear optical compound and nonlinear optical element comprising the same OGFOD1, OCIAD2, OCIAD1 BACE1 4124/4885SLC16A3 3538/4885SLC16A1 4423/4885
US-20120172599-A1 SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME OGFOD1, OCIAD2, OCIAD1 BACE1 4124/4885SLC16A3 3538/4885SLC16A1 4423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.