SCHEMBL10010049

SCHEMBL10010049

c1ccc2c(c1)CCCN2c1ccc2c(-c3ccc4ccccc4c3)c3cc(N4CCCc5ccccc54)ccc3c(-c3ccc4ccccc4c3)c2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ROCK1 Q13464 1/20 0.39
EED O75530 1/20 0.39
NUDT1 P36639 1/20 0.38
AKT1 P31749 1/20 0.38
PIK3CA P42336 1/20 0.38
OPRM1 P35372 1/20 0.36
RAB9A P51151 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
JAK2 O60674 1/20 0.36
JAK3 P52333 1/20 0.36
PTK2 Q05397 1/20 0.36
TP53 P04637 2/20 0.36
MAPT P10636 2/20 0.36
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
MAPK1 P28482 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13428242 1.00 ROCK1 (0.39) ROCK1EEDNUDT1AKT1PIK3CA
SCHEMBL13428448 0.96 ROCK1 (0.37) ROCK1EEDNUDT1AKT1PIK3CA
SCHEMBL13428243 0.96 ROCK1 (0.37) ROCK1EEDNUDT1AKT1PIK3CA
SCHEMBL13426577 0.96 ROCK1 (0.37) ROCK1EEDNUDT1AKT1PIK3CA
SCHEMBL13426642 0.96 ROCK1 (0.37) ROCK1EEDNUDT1AKT1PIK3CA
SCHEMBL13428257 0.95 EED (0.36) ROCK1EEDNUDT1AKT1PIK3CA
SCHEMBL13426673 0.95 EED (0.36) ROCK1EEDNUDT1AKT1PIK3CA
SCHEMBL13426526 0.95 EED (0.36) ROCK1EEDNUDT1AKT1PIK3CA
SCHEMBL13426631 0.95 EED (0.36) ROCK1EEDNUDT1AKT1PIK3CA
SCHEMBL13426669 0.95 EED (0.36) ROCK1EEDNUDT1AKT1PIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11785846-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-10-10 US disclosed
US-11785846-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-10-10 US disclosed
US-20230180604-A1 ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING AN ELECTRON BUFFER LAYER AND AN ELECTRON TRANSPORT LAYER DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2023-06-08 US disclosed
US-20230180604-A1 ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING AN ELECTRON BUFFER LAYER AND AN ELECTRON TRANSPORT LAYER DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2023-06-08 US disclosed
US-11588112-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-02-21 US disclosed
US-20220209137-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2022-06-30 US disclosed
US-11322692-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2022-05-03 US disclosed
US-10991889-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2021-04-27 US disclosed
US-20200381630-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2020-12-03 US disclosed
US-20200152885-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2020-05-14 US disclosed
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
EP-2141214-A2 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2010-01-06 EP disclosed
US-20090295281-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-12-03 US disclosed
US-20090295281-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-12-03 US disclosed
US-20090261714-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-10-22 US disclosed
US-20090261714-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-10-22 US disclosed
EP-2098532-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-09-09 EP disclosed
EP-2090637-A1 Organic electroluminescent compounds and light emitting diode using the same Gracel Display Inc. (KR) 2009-08-19 EP disclosed
US-20090189519-A1 Organic electroluminescent compounds and light emitting diode using the same GRACEL DISPLAY INC. (KR) 2009-07-30 US disclosed
US-20090189519-A1 Organic electroluminescent compounds and light emitting diode using the same GRACEL DISPLAY INC. (KR) 2009-07-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090189519-A1 Organic electroluminescent compounds and light emitting diode using the same OCIAD1, AOX1, OCIAD2 ROCK1 1717/4885EED 34/4885NUDT1 189/4885
US-20200381630-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ICOSLG, ELAVL1, SOD1 ROCK1 2745/4885EED 24/4885NUDT1 669/4885
US-20090261714-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same AOX1, ODC1, LEF1 ROCK1 2068/4885EED 457/4885NUDT1 446/4885
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same RPL36, RPL39, RPL36A ROCK1 3925/4885EED 1151/4885NUDT1 655/4885
US-20090295281-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same AOX1, LEF1, ODC1 ROCK1 2113/4885EED 489/4885NUDT1 457/4885
US-11322692-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ICOSLG, ELAVL1, SOD1 ROCK1 2745/4885EED 24/4885NUDT1 669/4885
US-10991889-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same OR10J3, EPCAM, L1CAM ROCK1 3176/4885EED 6/4885NUDT1 1142/4885
US-20200152885-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, EPCAM, L1CAM ROCK1 3176/4885EED 6/4885NUDT1 1142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.